{"id":"W2229044941","doi":"10.1007/s12010-015-1954-y","title":"Soluble Expression and Characterization of a New scFv Directed to Human CD123","year":2016,"lang":"en","type":"article","venue":"Applied Biochemistry and Biotechnology","topic":"Monoclonal and Polyclonal Antibodies Research","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; Sunnybrook Health Science Centre","funders":"Medical Research Council","keywords":"Phage display; Flow cytometry; Single-chain variable fragment; Antibody; Interleukin-3 receptor; Myeloid leukemia; Population; Molecular biology; Biology; Linker; Chemistry; Cancer research; Monoclonal antibody; Immunology; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004427793,0.00009673879,0.0001823715,0.00006381175,0.00005312508,0.000003931443,0.00005917372,0.0002505865,0.00005578369],"category_scores_gemma":[0.00002010568,0.00006066488,0.00001608917,0.0001161292,0.0002263552,0.00001185808,0.000148078,0.00008468024,0.00000492204],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008357304,"about_ca_system_score_gemma":0.00002466548,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001572766,"about_ca_topic_score_gemma":8.995601e-7,"domain_scores_codex":[0.9993626,0.000003318042,0.0001372168,0.0002465589,0.00008774873,0.0001624875],"domain_scores_gemma":[0.9996445,0.00001538088,0.00004199905,0.0001515076,0.00002417166,0.0001224027],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002170587,0.00003257435,0.0007951111,0.00008586924,0.00001340411,0.000002272577,0.00002366438,9.627609e-10,0.9701535,0.0004361166,0.0003217388,0.02791874],"study_design_scores_gemma":[0.0005889151,0.0001261849,0.003627349,0.000106135,0.000009138789,0.00002234842,0.00001998085,9.432524e-7,0.9875664,0.000199545,0.007653816,0.00007920345],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9931175,0.00007736631,0.00008130655,0.006084797,0.00001098667,0.000148224,0.00001127964,0.00006531597,0.0004032009],"genre_scores_gemma":[0.995405,0.0002545908,0.000554866,0.000100059,0.00006240355,0.000009020916,0.00002741791,0.000006751629,0.003579931],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02783954,"threshold_uncertainty_score":0.2473842,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01438760266430915,"score_gpt":0.2712621955827453,"score_spread":0.2568745929184362,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}