{"id":"W2229935667","doi":"10.1038/modpathol.2015.151","title":"Silent subtype 3 pituitary adenomas are not always silent and represent poorly differentiated monomorphous plurihormonal Pit-1 lineage adenomas","year":2016,"lang":"en","type":"article","venue":"Modern Pathology","topic":"Pituitary Gland Disorders and Treatments","field":"Medicine","cited_by":150,"is_retracted":false,"has_abstract":false,"ca_institutions":"University Health Network; University of Toronto","funders":"","keywords":"Pathology; Acromegaly; Corticotropic cell; Pituitary adenoma; Biology; Population; Adenoma; Medicine; Hormone; Internal medicine; Endocrinology; Pituitary gland","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001257496,0.0004523553,0.0007372044,0.0001916982,0.0001606273,0.00002006641,0.0001529649,0.0002940282,0.0002456596],"category_scores_gemma":[0.00007432608,0.0003031258,0.000177894,0.00008198434,0.0002290702,0.0001134896,0.0002140474,0.0002299249,0.0001461833],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001158027,"about_ca_system_score_gemma":0.00008054669,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001418946,"about_ca_topic_score_gemma":0.00007935832,"domain_scores_codex":[0.9974286,0.0001275265,0.0005012414,0.0009476496,0.0003159775,0.0006789814],"domain_scores_gemma":[0.9985024,0.0001208687,0.0001962196,0.0006865221,0.000100343,0.0003936529],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.003894867,0.003457463,0.8836396,0.0001635749,0.0007876429,0.01565342,0.001658645,0.00001565821,0.06353512,0.0002658997,0.003360065,0.02356801],"study_design_scores_gemma":[0.01048428,0.001488046,0.9785294,0.0001378218,0.0004144442,0.001312376,0.0001193827,0.0007619497,0.004026493,0.001535942,0.0006902926,0.0004995721],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9879996,0.005340671,0.001846708,0.002845434,0.0002557127,0.000638822,0.0002882019,0.0001658151,0.0006190398],"genre_scores_gemma":[0.9958791,0.0009393138,0.00021386,0.000764335,0.0001791264,0.0001020556,0.00018162,0.00006500426,0.001675655],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09488976,"threshold_uncertainty_score":0.9999421,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02141500044314809,"score_gpt":0.2395276746853821,"score_spread":0.218112674242234,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}