{"id":"W2230036583","doi":"10.4049/jimmunol.194.supp.143.6","title":"Retroviral transfer for a chimeric antigen receptor to generate regulatory T-like cells for the suppression of undesired immune responses. (VAC7P.1036)","year":2015,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"","keywords":"FOXP3; Adoptive cell transfer; Immune system; Immunology; Chimeric antigen receptor; Biology; Antigen; Autoimmunity; Antigen-presenting cell; Cell biology; T cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003713642,0.0005260111,0.0002750391,0.0003574523,0.0001611598,0.0004013674,0.0004406626,0.0007775986,0.002425131],"category_scores_gemma":[0.000149236,0.0002200069,0.0004147164,0.0002185634,0.0002825144,0.0001693481,0.0002277632,0.001105735,0.001588755],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000303736,"about_ca_system_score_gemma":0.0002148527,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003177498,"about_ca_topic_score_gemma":0.0002502569,"domain_scores_codex":[0.9997086,0.00005041358,0.00003068857,0.00005960418,0.00008648571,0.00006411687],"domain_scores_gemma":[0.9998578,0.00002795576,0.00004044173,0.00002335484,0.0000201527,0.00003035796],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005473346,0.00005207678,0.00005360949,0.00004394657,0.000006696921,0.0001047716,0.00001563207,0.0001345222,0.9973977,0.0003579212,0.000125936,0.001652505],"study_design_scores_gemma":[0.0001429059,0.000837569,0.0009095451,0.00001793498,0.00004040399,0.00130206,0.00001779955,0.003712184,0.9775712,0.0001050663,0.01533177,0.00001153806],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9379632,0.002986845,0.04897908,0.0004961467,0.0004755977,0.0007177788,0.002246595,0.001021912,0.005112896],"genre_scores_gemma":[0.9551659,0.0009739648,0.03030275,0.0002570138,0.00007101656,0.0004325631,0.002695194,0.000209912,0.00989168],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002425131,"threshold_uncertainty_score":0.008112907,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05798689285139266,"score_gpt":0.3217708482802225,"score_spread":0.2637839554288298,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}