{"id":"W2230135986","doi":"10.14232/phd.2233","title":"Rimonabant: a CB1 receptor antagonist as a direct interactional partner for μ- and δ-opioid receptor","year":2014,"lang":"en","type":"dissertation","venue":"","topic":"Pharmacological Receptor Mechanisms and Effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Institute of Genetics; Rheinische Friedrich-Wilhelms-Universität Bonn; Weizmann Institute of Science","keywords":"Rimonabant; Cannabinoid receptor; Opioid receptor; Antagonist; Opioid; Pharmacology; Psychology; Receptor; Medicine; Internal medicine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002555894,0.0004282942,0.000415387,0.00006276241,0.0002000931,0.00007794254,0.0001881523,0.0006044134,0.001149622],"category_scores_gemma":[0.0002527484,0.000357509,0.0002469217,0.00005286201,0.00004532084,0.000006384011,0.00004451073,0.0002116743,0.0001100844],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003023416,"about_ca_system_score_gemma":0.00010938,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000332288,"about_ca_topic_score_gemma":0.0000845925,"domain_scores_codex":[0.9982458,0.00008329045,0.0003128581,0.0007943155,0.0001800949,0.0003835989],"domain_scores_gemma":[0.9991034,0.0001058139,0.000203561,0.000199254,0.0001665432,0.000221382],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001488836,0.0001001606,0.0000155146,0.0001797953,0.0001634541,6.023519e-7,0.00004112131,5.915857e-7,0.8939717,0.000616572,0.0934797,0.009941924],"study_design_scores_gemma":[0.0005363142,0.0007328938,0.00003915072,0.00004463589,0.00005076387,0.000003053487,0.0000491149,0.00002026524,0.4838422,0.0001982171,0.5141464,0.0003370433],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9577168,0.001361505,0.0006692692,0.000227749,0.004922241,0.001654751,0.0003356672,0.00008738356,0.03302459],"genre_scores_gemma":[0.7728053,0.004078151,0.005005278,0.002328813,0.003843462,0.00198816,0.03006813,0.0002402395,0.1796425],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4206667,"threshold_uncertainty_score":0.9998877,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009557730594786013,"score_gpt":0.3062416821629534,"score_spread":0.2966839515681674,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}