{"id":"W2230483107","doi":"10.5858/134.6.907","title":"American Society of Clinical Oncology/College of American Pathologists Guideline Recommendations for Immunohistochemical Testing of Estrogen and Progesterone Receptors in Breast Cancer","year":2010,"lang":"en","type":"article","venue":"Archives of Pathology & Laboratory Medicine","topic":"Breast Cancer Treatment Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":896,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Canada's Michael Smith Genome Sciences Centre","funders":"National Cancer Institute","keywords":"Medicine; Breast cancer; Guideline; Estrogen receptor; Oncology; Internal medicine; Cancer; Progesterone receptor; Immunohistochemistry; Estrogen; Gynecology; Clinical trial; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.02069287,0.00155072,0.002175883,0.007478086,0.002048718,0.001870128,0.00750663,0.007750657,0.003932894],"category_scores_gemma":[0.0454841,0.0009986798,0.003530666,0.005741124,0.001827234,0.001568714,0.002093943,0.009924538,0.004823837],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.005105577,"about_ca_system_score_gemma":0.02253906,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.03233236,"about_ca_topic_score_gemma":0.0476853,"domain_scores_codex":[0.9759052,0.01007934,0.004919912,0.0006057455,0.007502567,0.0009872509],"domain_scores_gemma":[0.9262151,0.01339643,0.004854021,0.001483312,0.05129595,0.002755168],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009997577,0.0002649922,0.003651179,0.002694378,0.0001154424,0.0008573154,0.0004105367,0.001029631,0.001122454,0.003813488,0.8340482,0.1518925],"study_design_scores_gemma":[0.0005250339,0.0002579089,0.0225782,0.0186288,0.0006584264,0.004250863,0.0009882232,0.002803498,0.001456382,0.01256777,0.9350933,0.0001915892],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"methods","genre_scores_codex":[0.01131183,0.1094679,0.1136715,0.5542443,0.02472069,0.0224364,0.01227512,0.002004738,0.1498675],"genre_scores_gemma":[0.03677624,0.08769501,0.6377576,0.1450065,0.005534892,0.02249954,0.02568799,0.0005451251,0.03849718],"genre_candidate":"methods","genre_consensus":null,"teacher_disagreement_score":0.03233236,"threshold_uncertainty_score":0.1094357,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03289160724815034,"score_gpt":0.3886922636403727,"score_spread":0.3558006563922224,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}