{"id":"W2230733710","doi":"10.1189/jlb.3hi0814-393r","title":"The voltage-gated proton channel Hv1/VSOP inhibits neutrophil granule release","year":2015,"lang":"en","type":"article","venue":"Journal of Leukocyte Biology","topic":"Neutrophil, Myeloperoxidase and Oxidative Mechanisms","field":"Immunology and Microbiology","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children","funders":"Japan Society for the Promotion of Science","keywords":"Azurophilic granule; NADPH oxidase; Exocytosis; Granule (geology); Biology; Inflammation; Secretion; Cell biology; Respiratory burst; Granulocyte; Elastase; Reactive oxygen species; Biochemistry; Myeloperoxidase; Immunology; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001267028,0.000341799,0.0006422782,0.0002297886,0.0003676279,0.00003463506,0.0006627477,0.0004241949,0.0000651813],"category_scores_gemma":[0.0004110635,0.0002027941,0.000248193,0.0002719263,0.0004941624,0.0001901795,0.0001795236,0.0009149439,0.0004111603],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001525741,"about_ca_system_score_gemma":0.0004024603,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004261748,"about_ca_topic_score_gemma":0.00001358281,"domain_scores_codex":[0.9972761,0.0007498812,0.0009129237,0.00031079,0.00008791725,0.0006624095],"domain_scores_gemma":[0.997658,0.0002368533,0.0008557976,0.0003769122,0.0007240592,0.0001483853],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002428369,0.0001933919,0.0002496979,0.00001452064,0.0003486114,0.000119354,0.0003559827,0.00002009396,0.9788402,0.003351095,0.008901653,0.005176984],"study_design_scores_gemma":[0.003825127,0.00246569,0.0001790538,0.00004493568,0.00007042892,0.0009565373,0.0003222579,0.000005817807,0.7024516,0.004389593,0.2850437,0.0002452316],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9832019,0.008850521,0.0008652391,0.00263669,0.003186158,0.0006325275,0.00002293735,0.00005583931,0.000548169],"genre_scores_gemma":[0.9964509,0.0008372376,0.00006454753,0.0006988232,0.0004373435,0.00002513671,0.000035708,0.00003645153,0.001413859],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2763886,"threshold_uncertainty_score":0.8269703,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03121289819942809,"score_gpt":0.2627745030227244,"score_spread":0.2315616048232963,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}