{"id":"W2231115651","doi":"10.1038/ncomms8735","title":"Microbiota and host determinants of behavioural phenotype in maternally separated mice","year":2015,"lang":"en","type":"article","venue":"Nature Communications","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":535,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"Canadian Institutes of Health Research; Crohn's and Colitis Foundation of Canada; Ontario Ministry of Research and Innovation; Ministerio de Ciencia e Innovación; Crohn's and Colitis Foundation","keywords":"Gut–brain axis; Dysbiosis; Biology; Phenotype; Gut flora; Cholinergic; Anxiety; Maternal deprivation; Disease; Stressor; Host (biology); Immunology; Neuroscience; Physiology; Genetics; Psychology; Medicine; Internal medicine; Endocrinology; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001319588,0.00007348525,0.0001052804,0.0000412736,0.0000361263,0.000008766562,0.0003558377,0.0002210802,0.000001516895],"category_scores_gemma":[0.00003369406,0.00007222286,0.00001780451,0.00008509965,0.00008693785,0.000003312647,0.0002349177,0.0002113268,0.0000029177],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001302745,"about_ca_system_score_gemma":0.0000960149,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002070134,"about_ca_topic_score_gemma":0.003179932,"domain_scores_codex":[0.999504,0.0000672437,0.0001691544,0.0001167665,0.00003251148,0.0001102847],"domain_scores_gemma":[0.9992019,0.000008415856,0.0000764551,0.0005443583,0.0001173801,0.00005149908],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00002461453,0.00007084692,0.2577865,0.000009077193,0.00000527613,5.104417e-7,0.0001436891,3.507541e-7,0.7408109,0.00004465968,0.001001569,0.0001020082],"study_design_scores_gemma":[0.0008614409,0.0001150707,0.9029561,0.00004433724,0.00001754972,0.00003653975,0.000105509,0.00004148867,0.08409162,0.00001262212,0.01155394,0.000163833],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9929797,0.006204372,0.000001595565,0.0003170365,0.00005084604,0.0001125658,0.00004251313,0.000003975751,0.0002874004],"genre_scores_gemma":[0.9971624,0.000474343,0.001912031,0.0001842375,0.000009666738,0.000004011591,0.0001153252,0.000008787912,0.000129195],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6567193,"threshold_uncertainty_score":0.2945163,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03575251112922666,"score_gpt":0.3319993448223019,"score_spread":0.2962468336930753,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}