{"id":"W2231684654","doi":"10.1177/1060028015602274","title":"Adverse Drug Reactions Reported With Cholinesterase Inhibitors","year":2015,"lang":"en","type":"article","venue":"Annals of Pharmacotherapy","topic":"Pharmacovigilance and Adverse Drug Reactions","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":51,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Jewish General Hospital; Université Laval; Centre hospitalier universitaire de Québec","funders":"Canadian Institutes of Health Research; Top Institute Pharma; Novo Nordisk; College ter Beoordeling van Geneesmiddelen; GlaxoSmithKline; World Health Organization; Universiteit Utrecht","keywords":"Medicine; Pharmacovigilance; Rivastigmine; Donepezil; Galantamine; Adverse drug reaction; Disease; Adverse effect; Dementia; Pharmacology; Drug; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001021879,0.0003655454,0.0004205161,0.0002956434,0.0001873111,0.00001348644,0.0002898453,0.0001524241,0.0008946786],"category_scores_gemma":[0.00005448513,0.0003179264,0.0002049153,0.0006704489,0.0002883328,0.0006364248,0.00003274125,0.0007734603,0.0001614421],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004389996,"about_ca_system_score_gemma":0.0003185824,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001293303,"about_ca_topic_score_gemma":0.00001259311,"domain_scores_codex":[0.9975681,0.0003192922,0.000726279,0.0004345904,0.0003823083,0.0005694211],"domain_scores_gemma":[0.9976024,0.000188147,0.0005641863,0.0003470423,0.0005869214,0.0007113092],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.004009516,0.002205385,0.01852214,0.00008887204,0.001464196,0.000388291,0.002599653,0.01052848,0.7127495,0.0003197122,0.2378557,0.009268606],"study_design_scores_gemma":[0.003384963,0.00009026536,0.0002246485,0.00002948446,0.0001117427,0.00007823607,0.0003339404,0.0004759782,0.4810247,0.0001056034,0.5138679,0.0002726065],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9782497,0.0007376411,0.00005211954,0.004601108,0.001524932,0.0006027204,0.000120976,0.0002722797,0.01383854],"genre_scores_gemma":[0.9849322,0.001889614,0.0001557958,0.007900187,0.0007063588,0.00009476465,0.00005704397,0.00006377461,0.004200271],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2760122,"threshold_uncertainty_score":0.9999273,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.3178635584416977,"score_gpt":0.5096920044994403,"score_spread":0.1918284460577426,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}