{"id":"W2233683956","doi":"10.1016/j.celrep.2015.12.079","title":"PI5P Triggers ICAM-1 Degradation in Shigella Infected Cells, Thus Dampening Immune Cell Recruitment","year":2016,"lang":"en","type":"article","venue":"Cell Reports","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Fondation pour la Recherche Médicale; Institut National de la Santé et de la Recherche Médicale; Agence Nationale de la Recherche; Advanced Foods and Materials Canada","keywords":"Shigella; Shigella flexneri; Internalization; Immune system; Microbiology; Cell biology; Biology; Pathogen; Secretion; Cell; Immunology; Bacteria; Salmonella; Biochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009542729,0.0003173777,0.0003030029,0.00009535098,0.0001334647,0.0003200492,0.0001402452,0.0002988264,0.00137203],"category_scores_gemma":[0.00009451515,0.00009108946,0.0002239594,0.00008583048,0.0001973955,0.0002366359,0.0002384621,0.0006204149,0.0003331161],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002701629,"about_ca_system_score_gemma":0.0001786029,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003160206,"about_ca_topic_score_gemma":0.0003107562,"domain_scores_codex":[0.9998941,0.00001358565,0.000008143229,0.00002117653,0.00002503991,0.00003790218],"domain_scores_gemma":[0.9999567,0.000009783713,0.00001015803,0.000007694536,0.000006503587,0.000009140041],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006574678,0.00001005534,0.00007886358,0.00004022214,0.000002479573,0.00005889329,0.00001101632,0.00002123913,0.9988515,0.00006102409,0.0000235542,0.0007753521],"study_design_scores_gemma":[0.000007408054,0.0001235764,0.001963613,0.000003893133,0.000006006685,0.0001636876,0.00001953636,0.0003039755,0.9964641,0.00003368389,0.0009087589,0.000001771179],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9911686,0.002498033,0.004311186,0.0002002284,0.00004576326,0.00002015735,0.0001820404,0.00009467749,0.001479302],"genre_scores_gemma":[0.9948815,0.001141307,0.00218432,0.00005565949,0.00001272709,0.00002752182,0.000247253,0.00001188998,0.001437943],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00137203,"threshold_uncertainty_score":0.004589915,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01851764647509304,"score_gpt":0.2353885998846627,"score_spread":0.2168709534095697,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}