{"id":"W2234174166","doi":"10.1371/journal.pgen.1005792","title":"Chromosomal Integrity after UV Irradiation Requires FANCD2-Mediated Repair of Double Strand Breaks","year":2016,"lang":"en","type":"article","venue":"PLoS Genetics","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Fondo para la Investigación Científica y Tecnológica; Ministerio de Ciencia, Tecnología e Innovación Productiva; Consejo Nacional de Investigaciones Científicas y Técnicas; Universitat Autònoma de Barcelona; York University; Nuclear Regulation Authority","keywords":"FANCD2; Biology; Fanconi anemia; DNA repair; DNA damage; Homologous recombination; DNA; Chromatid; Molecular biology; Homologous chromosome; DNA replication; Cell biology; Genome instability; Genetics; Gene; Chromosome","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000914169,0.0002954666,0.0001869404,0.0002015423,0.0001683496,0.0003745818,0.0002165531,0.0003598906,0.001096494],"category_scores_gemma":[0.0001067611,0.0001389292,0.0001459456,0.0001331786,0.000224229,0.0001961628,0.0002890333,0.0003122786,0.0003580253],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003602684,"about_ca_system_score_gemma":0.000190797,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006309421,"about_ca_topic_score_gemma":0.0006775244,"domain_scores_codex":[0.999887,0.00001788781,0.000009041701,0.00003374646,0.00002937215,0.00002302221],"domain_scores_gemma":[0.9999053,0.00001289824,0.00003171514,0.00001468026,0.000009884438,0.00002550071],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004621671,0.000006183473,0.0001553727,0.00001885039,0.00000238885,0.00006519639,0.000005778507,0.00004053664,0.9988086,0.0001086128,0.00003463991,0.0007076391],"study_design_scores_gemma":[0.000008379189,0.0000743068,0.01216658,0.00000912475,0.000008627696,0.0006934004,0.00001980881,0.0007278477,0.9824939,0.0001015516,0.003688903,0.000007481945],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9878914,0.003517306,0.004775502,0.0001460632,0.00004412918,0.00002227525,0.0006704865,0.0003003902,0.00263237],"genre_scores_gemma":[0.9952264,0.0007500882,0.0008787754,0.0000327368,0.000006936341,0.00001649441,0.0004412635,0.00003152188,0.002615868],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001096494,"threshold_uncertainty_score":0.003668129,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01530788026093399,"score_gpt":0.2396053618013183,"score_spread":0.2242974815403843,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}