{"id":"W2234666218","doi":"10.1016/j.radonc.2015.12.020","title":"Dose-escalation of five-fraction SABR in prostate cancer: Toxicity comparison of two prospective trials","year":2016,"lang":"en","type":"article","venue":"Radiotherapy and Oncology","topic":"Prostate Cancer Diagnosis and Treatment","field":"Medicine","cited_by":64,"is_retracted":false,"has_abstract":false,"ca_institutions":"Health Sciences Centre; Sunnybrook Health Science Centre; CancerCare Manitoba; University of Toronto","funders":"Canadian Association of Radiation Oncology; Abbott Canada; American Society for Radiation Oncology","keywords":"Medicine; SABR volatility model; Prostate cancer; Toxicity; Urology; Prostate; Genitourinary system; Prospective cohort study; Radiation therapy; Prostate-specific antigen; Cumulative dose; Internal medicine; Surgery; Nuclear medicine; Gastroenterology; Cancer","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004080326,0.00009605615,0.0008194001,0.00009473886,0.00001815819,0.000001860963,0.00002148224,0.00007060421,0.00009469192],"category_scores_gemma":[0.00005615491,0.00005922324,0.00005884317,0.0001069052,0.0001094906,0.00006647388,0.000005628452,0.00006000105,3.481071e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008452649,"about_ca_system_score_gemma":0.0001601951,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004944926,"about_ca_topic_score_gemma":0.000587697,"domain_scores_codex":[0.9989572,0.0001632263,0.0004840241,0.0001853109,0.0000892935,0.0001209279],"domain_scores_gemma":[0.9990111,0.0004021463,0.0003759171,0.00009412845,0.00007240774,0.00004430186],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00300825,0.0006807007,0.6571401,0.0000477459,0.0001276938,0.000003274601,0.00121921,0.00002180606,0.06405629,0.0002142827,0.0001165288,0.2733641],"study_design_scores_gemma":[0.02166448,0.004811163,0.7890138,0.0003225449,0.0001059226,0.000007316074,0.0001391267,0.0002390103,0.1800977,0.0006740388,0.00283263,0.0000922833],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9912227,0.004962768,0.0001891197,0.002252419,0.0001190622,0.001045738,0.00003680889,0.000009236512,0.0001620881],"genre_scores_gemma":[0.9884772,0.0106052,0.0005022671,0.00008577689,0.00008360545,0.0001602251,0.000003996543,0.000008431492,0.00007332823],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2732719,"threshold_uncertainty_score":0.2415054,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04127540079158976,"score_gpt":0.4080867225123937,"score_spread":0.3668113217208039,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}