{"id":"W2235725807","doi":"","title":"Pharmacokinetics studies and toxicity profile of raltitrexed used by intraperitoneal route in normothermia in a pig model.","year":2003,"lang":"en","type":"article","venue":"PubMed","topic":"Intraperitoneal and Appendiceal Malignancies","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Hôpital Maisonneuve-Rosemont","funders":"","keywords":"Raltitrexed; Medicine; Pharmacokinetics; Toxicity; Exploratory laparotomy; Laparotomy; Cmax; Blood sampling; Anesthesia; Pharmacology; Gastroenterology; Surgery; Chemotherapy; Internal medicine; Fluorouracil","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003067677,0.0001680302,0.0004653848,0.0001132566,0.0000218137,0.000007374328,0.00005650408,0.00007710916,0.00001672954],"category_scores_gemma":[0.00008924717,0.0001406401,0.00003688182,0.0002553595,0.0001598685,0.00007778525,0.0000278375,0.0001745735,8.083266e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007436462,"about_ca_system_score_gemma":0.00004052226,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009237613,"about_ca_topic_score_gemma":0.00007996764,"domain_scores_codex":[0.9987398,0.00005576278,0.0003775801,0.0002374208,0.0001852709,0.0004041863],"domain_scores_gemma":[0.999622,0.00004860454,0.00007422199,0.0001132019,0.00004006483,0.0001018653],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002173788,0.002514974,0.2819328,0.002408301,0.0004182173,0.0003271901,0.01316026,0.0002818283,0.6015325,0.002313212,0.003154748,0.08978225],"study_design_scores_gemma":[0.01355232,0.0003311118,0.1796894,0.0003755433,0.000156329,0.00008029919,0.001815465,0.005539731,0.7957569,0.0008099357,0.001169125,0.0007238209],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9946174,0.001867796,0.000009254349,0.0004666226,0.00006481764,0.0009903077,0.0000260478,0.00002092776,0.001936801],"genre_scores_gemma":[0.9977891,0.0004010006,0.0004670407,0.0002748234,0.00002384166,0.0005118759,0.000005746681,0.00001736863,0.0005091865],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1942245,"threshold_uncertainty_score":0.5735137,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03223271980172943,"score_gpt":0.2763124222638833,"score_spread":0.2440797024621538,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}