{"id":"W2235725807","doi":"","title":"Pharmacokinetics studies and toxicity profile of raltitrexed used by intraperitoneal route in normothermia in a pig model.","year":2003,"lang":"en","type":"article","venue":"PubMed","topic":"Intraperitoneal and Appendiceal Malignancies","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Hôpital Maisonneuve-Rosemont","funders":"","keywords":"Raltitrexed; Medicine; Pharmacokinetics; Toxicity; Exploratory laparotomy; Laparotomy; Cmax; Blood sampling; Anesthesia; Pharmacology; Gastroenterology; Surgery; Chemotherapy; Internal medicine; Fluorouracil","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004245049,0.000382451,0.0004491745,0.0002572965,0.0001151463,0.0002856818,0.0002660666,0.0004510977,0.001017482],"category_scores_gemma":[0.0002544056,0.0001620627,0.0003395204,0.0001418984,0.0003876086,0.0005052289,0.00009554019,0.0007132184,0.0003094675],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002487136,"about_ca_system_score_gemma":0.0002527452,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003929924,"about_ca_topic_score_gemma":0.0004522921,"domain_scores_codex":[0.9998235,0.00004745016,0.00001125946,0.00003257313,0.00004593561,0.00003945275],"domain_scores_gemma":[0.9997212,0.00004564219,0.0001188533,0.00003427952,0.00002886598,0.00005120187],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002966877,0.001132359,0.001162309,0.0001177302,0.00002130429,0.0001496525,0.00005345641,0.0002620986,0.9876084,0.00005639869,0.0001491554,0.006320232],"study_design_scores_gemma":[0.0004962024,0.1729229,0.02401249,0.00003819564,0.0002007391,0.00123807,0.0001418281,0.002479341,0.7934403,0.0001125771,0.004873836,0.00004357173],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9943803,0.001865317,0.002572773,0.00009977275,0.0000438466,0.0001294846,0.0002311346,0.00005731621,0.000620114],"genre_scores_gemma":[0.9917703,0.00213003,0.00313515,0.0001580551,0.00005215775,0.0002426038,0.0006582962,0.0000194245,0.001834121],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001017482,"threshold_uncertainty_score":0.003403842,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03223271980172943,"score_gpt":0.2763124222638833,"score_spread":0.2440797024621538,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}