{"id":"W2235735847","doi":"10.1016/j.devcel.2015.12.016","title":"SAPCD2 Controls Spindle Orientation and Asymmetric Divisions by Negatively Regulating the Gαi-LGN-NuMA Ternary Complex","year":2016,"lang":"en","type":"article","venue":"Developmental Cell","topic":"Microtubule and mitosis dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":42,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; Lunenfeld-Tanenbaum Research Institute; Université de Montréal; Montreal Clinical Research Institute; University of Toronto","funders":"Canadian Institutes of Health Research; W. Garfield Weston Foundation; Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs; Fondation Brain Canada","keywords":"Biology; Cell biology; Spindle apparatus; Cell division; Morphogenesis; Mitosis; Asymmetric cell division; Regulator; Cell; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001200967,0.0001450157,0.000105603,0.00003425721,0.0002065879,0.00003366662,0.0001388291,0.00007379852,0.00002961405],"category_scores_gemma":[0.00003787734,0.00009141667,0.00003730125,0.00009382013,0.00009059456,0.000008804524,0.0001701133,0.00004667108,0.00001940859],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003301993,"about_ca_system_score_gemma":0.00003622892,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002476501,"about_ca_topic_score_gemma":0.00001758972,"domain_scores_codex":[0.9991384,0.00004860362,0.0001990315,0.0002942135,0.0001131116,0.0002066401],"domain_scores_gemma":[0.9996313,0.0000422007,0.00009698965,0.0001283043,0.0000375795,0.00006363633],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002517448,0.00003475093,0.0100546,0.000005738388,0.00002351485,6.74903e-7,0.0001016438,4.940912e-7,0.9635277,0.00003101106,0.00542853,0.02076619],"study_design_scores_gemma":[0.002318578,0.000207296,0.08089176,0.00003455033,0.00002158108,0.00003081376,0.0005250903,0.00009465091,0.8391322,0.000112957,0.07621809,0.0004124037],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9914979,0.0003209204,0.00465322,0.0002357302,0.0000732133,0.0002552468,0.00007021926,0.00001034248,0.00288322],"genre_scores_gemma":[0.9946852,0.0001647672,0.002409593,0.0004319181,0.0000487523,0.00001505858,0.0001776998,0.00001779751,0.00204916],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1243954,"threshold_uncertainty_score":0.3727864,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009460281478565815,"score_gpt":0.2262368499528521,"score_spread":0.2167765684742863,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}