{"id":"W2236102963","doi":"10.1371/journal.pone.0147059","title":"Increased Engraftment of Human Short Term Repopulating Hematopoietic Cells in NOD/SCID/IL2rγnull Mice by Lentiviral Expression of NUP98-HOXA10HD","year":2016,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency","funders":"National Cancer Institute; National Heart, Lung, and Blood Institute; American Lebanese Syrian Associated Charities","keywords":"Haematopoiesis; Stem cell; Biology; CD34; Transplantation; Hematopoietic stem cell; Immunology; Viral vector; Cancer research; Genetic enhancement; Fusion gene; Cell biology; Gene; Medicine; Genetics; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003282223,0.0004405,0.0002794549,0.0004531633,0.0001179425,0.0003560747,0.0002033667,0.0003347627,0.002448732],"category_scores_gemma":[0.0001025421,0.000134532,0.0002596744,0.0001826116,0.0003348776,0.0002780182,0.0002815032,0.0008306499,0.000401429],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001261442,"about_ca_system_score_gemma":0.000146919,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002064991,"about_ca_topic_score_gemma":0.0003162957,"domain_scores_codex":[0.9998349,0.0000236082,0.00002697087,0.00004523625,0.00004451077,0.00002478688],"domain_scores_gemma":[0.9998387,0.00003152072,0.00004680949,0.00003507495,0.000008039618,0.00003982799],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005996374,0.00004249617,0.00009963015,0.00001917807,0.000002777832,0.00002941329,0.00001316954,0.00003115795,0.9987161,0.00007128549,0.00001418711,0.0009005441],"study_design_scores_gemma":[0.00001495493,0.0004203902,0.001453155,0.000005237012,0.0000115651,0.0002226925,0.00001667964,0.0003360226,0.99562,0.00003580534,0.001861059,0.000002633192],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9841377,0.001191786,0.01153509,0.0001108539,0.00005504855,0.0001022998,0.0006528134,0.000237365,0.001977049],"genre_scores_gemma":[0.9809003,0.0008957508,0.01075035,0.0000475315,0.00001395845,0.0001266535,0.001161993,0.00006524589,0.006038188],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002448732,"threshold_uncertainty_score":0.008191824,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03121395546697494,"score_gpt":0.2808301658725477,"score_spread":0.2496162104055727,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}