{"id":"W2236581178","doi":"10.1371/journal.pone.0146273","title":"Generation of a Conditional Allele of the Transcription Factor Atonal Homolog 8 (Atoh8)","year":2016,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; Child and Family Research Institute","funders":"Ministerio de Ciencia e Innovación; National Institute of Diabetes and Digestive and Kidney Diseases; Instituto de Salud Carlos III; Ministerio de Economía y Competitividad; Generalitat de Catalunya","keywords":"Biology; Conditional gene knockout; Transgene; Pancreas; Cellular differentiation; Cre recombinase; Knockout mouse; Cell biology; Genetics; Genetically modified mouse; Gene; Endocrinology; Phenotype","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004004857,0.000716185,0.0004772007,0.00102265,0.0004771807,0.000471793,0.001041021,0.0008950513,0.005287966],"category_scores_gemma":[0.0002768277,0.0005789329,0.000621724,0.000412497,0.000737837,0.0004405844,0.0008208108,0.001690484,0.001753435],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004082361,"about_ca_system_score_gemma":0.0004692437,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009519994,"about_ca_topic_score_gemma":0.001659205,"domain_scores_codex":[0.9994399,0.00003577723,0.00008592094,0.0001767989,0.0001835639,0.00007796482],"domain_scores_gemma":[0.99913,0.0001033606,0.0002614879,0.00009737963,0.0000716272,0.0003363112],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001614901,0.00005700729,0.0003362361,0.00005360603,0.0000116683,0.0002265539,0.00004718734,0.0000664746,0.9971392,0.0004234954,0.0001117003,0.00136539],"study_design_scores_gemma":[0.0001844487,0.0005417284,0.007546329,0.00005176756,0.0001102199,0.001981749,0.0001289977,0.001898918,0.971419,0.000218643,0.01588604,0.0000321717],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9562095,0.000977948,0.0315396,0.0003249669,0.0002420621,0.0004937905,0.005927932,0.0006446542,0.003639544],"genre_scores_gemma":[0.9150001,0.001982398,0.03259311,0.0003164715,0.00007653959,0.001002942,0.007663145,0.000777718,0.04058759],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005287966,"threshold_uncertainty_score":0.01769006,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.11225946975091,"score_gpt":0.2454855404574165,"score_spread":0.1332260707065065,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}