{"id":"W2237079496","doi":"10.3390/ijms17010080","title":"Obesity and Its Potential Effects on Antidepressant Treatment Outcomes in Patients with Depressive Disorders: A Literature Review","year":2016,"lang":"en","type":"review","venue":"International Journal of Molecular Sciences","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":78,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; University Health Network","funders":"National Institute of Mental Health; H. Lundbeck A/S; Pfizer; Eli Lilly and Company; Bristol-Myers Squibb; Sunovion; Brain and Behavior Research Foundation","keywords":"Antidepressant; Obesity; Neurocognitive; Major depressive disorder; Medicine; Depression (economics); Internal medicine; Psychiatry; Psychology; Clinical psychology; Cognition","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001039963,0.0007730334,0.00189828,0.003053167,0.0002629461,0.0009160766,0.0008336973,0.0008984323,0.002788581],"category_scores_gemma":[0.002753826,0.0003002243,0.001118516,0.003419578,0.000285083,0.0008334916,0.0005515563,0.0007064393,0.0003576575],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004934006,"about_ca_system_score_gemma":0.001907216,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002059778,"about_ca_topic_score_gemma":0.00477629,"domain_scores_codex":[0.9996352,0.00008468369,0.0001378067,0.00004978463,0.00007565738,0.00001693076],"domain_scores_gemma":[0.9982103,0.001257974,0.0002799944,0.00001894128,0.0001921088,0.00004072701],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"systematic_review","study_design_scores_codex":[0.0001754209,0.00006779966,0.001188162,0.1589038,0.0009117471,0.0002298343,0.000142024,0.0002086086,0.0003037026,0.000809679,0.010174,0.8268853],"study_design_scores_gemma":[0.0001937925,0.000574365,0.02604187,0.3478709,0.01328974,0.006428352,0.0007220972,0.0004329904,0.0006562861,0.00362257,0.6000501,0.000116863],"study_design_candidate":"systematic_review","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001197903,0.9995977,0.00001982503,0.0001006347,0.00003246964,0.000003901702,0.00001973002,0.00000121078,0.0001046567],"genre_scores_gemma":[0.0007571397,0.9990363,0.00006458079,0.00005032435,0.00003922327,0.000005273839,0.00001777875,2.864178e-7,0.00002913628],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003053167,"threshold_uncertainty_score":0.009328723,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0120761241527578,"score_gpt":0.3027371984866544,"score_spread":0.2906610743338965,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}