{"id":"W2237540193","doi":"10.1152/ajpregu.2000.279.2.r666","title":"Role and mechanism of PKC in ischemic preconditioning of pig skeletal muscle against infarction","year":2000,"lang":"en","type":"article","venue":"American Journal of Physiology-Regulatory, Integrative and Comparative Physiology","topic":"Cardiac Ischemia and Reperfusion","field":"Medicine","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Hospital for Sick Children","funders":"","keywords":"Chelerythrine; Protein kinase C; Ischemia; Ischemic preconditioning; Skeletal muscle; Pharmacology; Infarction; Medicine; Western blot; Phorbol; Chemistry; Myocardial infarction; Internal medicine; Endocrinology; Biochemistry; Kinase","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002703771,0.0003923493,0.0003505395,0.0001997486,0.0002034252,0.0002862743,0.0002597733,0.0004700143,0.0007465375],"category_scores_gemma":[0.000146439,0.0002450317,0.0003537633,0.0001324614,0.0004061962,0.0004064167,0.0002415239,0.0005421382,0.0003252962],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000345828,"about_ca_system_score_gemma":0.0002908352,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003318536,"about_ca_topic_score_gemma":0.0002505458,"domain_scores_codex":[0.9998753,0.0000253152,0.00001171257,0.0000242328,0.00001646836,0.00004701195],"domain_scores_gemma":[0.999911,0.00001178888,0.00003254638,0.00001226852,0.000009440607,0.00002301526],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009312102,0.00006031834,0.0004363075,0.00009202986,0.000005771201,0.000116475,0.00002187673,0.00008843017,0.9959754,0.000194341,0.00002889346,0.002048969],"study_design_scores_gemma":[0.0003022572,0.002383076,0.0244066,0.00004681891,0.00008531787,0.0006258169,0.00008197947,0.001483849,0.9685946,0.0002876552,0.001692414,0.000009658708],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9855439,0.009391151,0.003080961,0.0002739512,0.00005116397,0.00007375253,0.00009602013,0.00005986325,0.001429324],"genre_scores_gemma":[0.9922572,0.004814367,0.001276448,0.0001263192,0.00004881958,0.0000896958,0.0001584584,0.000008122671,0.001220516],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007465375,"threshold_uncertainty_score":0.002509177,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008498229048094877,"score_gpt":0.2572505329007367,"score_spread":0.2487523038526419,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}