{"id":"W2237548841","doi":"10.1038/ncb3290","title":"Chronic inflammation imposes aberrant cell fate in regenerating epithelia through mechanotransduction","year":2015,"lang":"en","type":"article","venue":"Nature Cell Biology","topic":"Corneal Surgery and Treatments","field":"Medicine","cited_by":156,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Institute of Genetics; Associazione Italiana per la Ricerca sul Cancro; École Polytechnique Fédérale de Lausanne; European Commission; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; National Science Foundation","keywords":"Inflammation; Mechanotransduction; Cell biology; Biology; Wound healing; Progenitor cell; Epithelium; Regeneration (biology); Stem cell; Corneal epithelium; Immunology; Pathology; Medicine; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002032184,0.0001567279,0.0002551962,0.00008152473,0.00004012057,0.000005798332,0.00004624968,0.000485026,0.00004398303],"category_scores_gemma":[0.00003885586,0.0001207549,0.00006303404,0.0001930618,0.00003010235,0.0000826505,0.00001651104,0.0004317581,0.00005314847],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001967238,"about_ca_system_score_gemma":0.0001272008,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000139082,"about_ca_topic_score_gemma":0.000133365,"domain_scores_codex":[0.9990186,0.0001028581,0.0002516019,0.0002886851,0.00008428456,0.0002539837],"domain_scores_gemma":[0.9995419,0.00004523567,0.00009522874,0.0001772583,0.00007358004,0.00006683649],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002853866,0.0001558363,0.02212802,0.0001126703,0.0000347073,0.00007119135,0.0007924046,0.0001876893,0.947477,0.0006870451,0.0002171632,0.0278509],"study_design_scores_gemma":[0.002544938,0.0004867008,0.002111519,0.00005128948,0.00005184941,0.0000295495,0.00006198966,0.0002165692,0.9801224,0.0009049558,0.01326679,0.0001514871],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9846945,0.00976518,0.0001070761,0.0007691819,0.0008651959,0.0003195337,0.000008699372,0.00005308038,0.003417565],"genre_scores_gemma":[0.9977249,0.0003819371,0.0005774803,0.0001360284,0.0005145411,0.00002264687,0.000253178,0.0000142357,0.0003750824],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03264538,"threshold_uncertainty_score":0.4924242,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0217818479364996,"score_gpt":0.2838576864748627,"score_spread":0.2620758385383631,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}