{"id":"W2237548841","doi":"10.1038/ncb3290","title":"Chronic inflammation imposes aberrant cell fate in regenerating epithelia through mechanotransduction","year":2015,"lang":"en","type":"article","venue":"Nature Cell Biology","topic":"Corneal Surgery and Treatments","field":"Medicine","cited_by":156,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Institute of Genetics; Associazione Italiana per la Ricerca sul Cancro; École Polytechnique Fédérale de Lausanne; European Commission; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; National Science Foundation","keywords":"Inflammation; Mechanotransduction; Cell biology; Biology; Wound healing; Progenitor cell; Epithelium; Regeneration (biology); Stem cell; Corneal epithelium; Immunology; Pathology; Medicine; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003797963,0.0002378064,0.0002856023,0.0003876852,0.0004027524,0.001013523,0.0002041516,0.0005005656,0.001747177],"category_scores_gemma":[0.0002474041,0.0002272799,0.0002781428,0.000240321,0.0006109841,0.000636543,0.0005414839,0.0009081919,0.0003498616],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002965356,"about_ca_system_score_gemma":0.0003235376,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000236213,"about_ca_topic_score_gemma":0.0005398749,"domain_scores_codex":[0.9994521,0.0001063548,0.00004657263,0.00005667674,0.0001285441,0.0002097981],"domain_scores_gemma":[0.9997864,0.00002735532,0.00006585723,0.00003944433,0.00002901054,0.00005194941],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003697971,0.00004209745,0.001733048,0.00006221593,0.00000887789,0.0001708382,0.00008384101,0.00006772619,0.9932811,0.0009487484,0.0001315191,0.003100253],"study_design_scores_gemma":[0.0001033117,0.001570549,0.07717526,0.00007401965,0.00008056801,0.002193342,0.001488138,0.002017638,0.9044462,0.002870145,0.007941059,0.00003981325],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9933612,0.002668875,0.002024614,0.0002809306,0.00005822852,0.00001063574,0.00009425048,0.0000426644,0.001458551],"genre_scores_gemma":[0.9969326,0.001080297,0.0007431174,0.0001081897,0.00002202768,0.00001258827,0.00006357674,0.00001277812,0.00102473],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001747177,"threshold_uncertainty_score":0.005844951,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0217818479364996,"score_gpt":0.2838576864748627,"score_spread":0.2620758385383631,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}