{"id":"W2240173075","doi":"10.1038/cdd.2015.160","title":"NDPK-D (NM23-H4)-mediated externalization of cardiolipin enables elimination of depolarized mitochondria by mitophagy","year":2016,"lang":"en","type":"article","venue":"Cell Death and Differentiation","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":241,"is_retracted":false,"has_abstract":false,"ca_institutions":"McMaster University","funders":"National Institute for Occupational Safety and Health; National Institute of Neurological Disorders and Stroke; National Institute of Allergy and Infectious Diseases; National Heart, Lung, and Blood Institute; National Institute on Aging; Barth Syndrome Foundation; National Institutes of Health; Groupement des Entreprises Françaises dans la lutte contre le Cancer; Fondation pour la Recherche Médicale; National Institute of Environmental Health Sciences; U.S. Department of Veterans Affairs","keywords":"Mitophagy; Cardiolipin; Cell biology; Mitochondrion; Chemistry; Mitochondrial fission; Biology; Biochemistry; Autophagy; Phospholipid; Apoptosis; Membrane","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001816686,0.0002651818,0.0002324932,0.0001664324,0.0002814013,0.000379192,0.0003353156,0.0003420967,0.002025426],"category_scores_gemma":[0.0001768572,0.000130588,0.0002580576,0.0001564119,0.0003282073,0.0004472084,0.0004082419,0.0006660454,0.0004569438],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006252737,"about_ca_system_score_gemma":0.0003502,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007427252,"about_ca_topic_score_gemma":0.000946584,"domain_scores_codex":[0.9998156,0.00002828728,0.00001842851,0.00004608215,0.00003453649,0.00005693024],"domain_scores_gemma":[0.9999113,0.00001737927,0.00002156966,0.00002036024,0.000006776026,0.00002252274],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003640505,0.00004087479,0.00007802039,0.00002839201,0.000007905447,0.00006718188,0.0000142219,0.0000756937,0.9978325,0.000343227,0.00009554765,0.001052408],"study_design_scores_gemma":[0.00001991234,0.00004312426,0.0005570587,0.000001713148,0.000004117463,0.00007560715,0.000009807707,0.000387487,0.9975502,0.00005169588,0.001296582,0.000002790575],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9891828,0.0007059058,0.005917316,0.0003168435,0.00008218227,0.00005146328,0.0004758752,0.0001440091,0.003123747],"genre_scores_gemma":[0.994948,0.0002993788,0.002181666,0.0000518951,0.00000817058,0.00003197042,0.0003219231,0.00002632598,0.00213062],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002025426,"threshold_uncertainty_score":0.006775737,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006623022092947082,"score_gpt":0.2220395020827183,"score_spread":0.2154164799897713,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}