{"id":"W2241247270","doi":"10.1093/carcin/bgv148","title":"The retinoic acid derivative, ABPN, inhibits pancreatic cancer through induction of Nrdp1","year":2015,"lang":"en","type":"article","venue":"Carcinogenesis","topic":"Retinoids in leukemia and cellular processes","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"National Cancer Institute","keywords":"Retinoic acid; Medicine; Cancer research; Pancreatic cancer; Tretinoin; Internal medicine; Oncology; Cancer; Pharmacology; Chemistry; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002258833,0.0001633961,0.0001710648,0.00001917564,0.0001280533,0.00001864817,0.0002449159,0.0001550544,0.000008132492],"category_scores_gemma":[0.0002495661,0.0001191743,0.000083212,0.0001976956,0.0002212673,0.000007647577,0.0001030046,0.00007311954,0.000005172605],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004044067,"about_ca_system_score_gemma":0.0003026879,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009518534,"about_ca_topic_score_gemma":0.00002173888,"domain_scores_codex":[0.9989008,0.0001051791,0.0002562977,0.000291311,0.0002127857,0.0002336592],"domain_scores_gemma":[0.9989819,0.00001791641,0.0001650293,0.0004016889,0.0003632164,0.00007025173],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009318638,0.00001414011,0.01883214,0.00005148326,0.00006532363,8.905894e-7,0.0002824632,0.0000369325,0.9757642,0.0001020863,0.002181564,0.00257556],"study_design_scores_gemma":[0.0003391523,0.0001300205,0.002084336,0.00002492316,0.00005059337,0.00001140312,0.0005663858,0.000007739461,0.9827355,0.000251867,0.01364886,0.0001492868],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9759703,0.02094519,0.0005777779,0.000158603,0.0002748675,0.0001528406,0.000009987215,0.00001208763,0.00189836],"genre_scores_gemma":[0.9962389,0.002294325,0.0002992951,0.000102302,0.0003166206,0.00005578069,0.00003209276,0.00002679065,0.0006339356],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02026857,"threshold_uncertainty_score":0.4859786,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03169583968621449,"score_gpt":0.2775752157047022,"score_spread":0.2458793760184877,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}