{"id":"W2241247270","doi":"10.1093/carcin/bgv148","title":"The retinoic acid derivative, ABPN, inhibits pancreatic cancer through induction of Nrdp1","year":2015,"lang":"en","type":"article","venue":"Carcinogenesis","topic":"Retinoids in leukemia and cellular processes","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"National Cancer Institute","keywords":"Retinoic acid; Medicine; Cancer research; Pancreatic cancer; Tretinoin; Internal medicine; Oncology; Cancer; Pharmacology; Chemistry; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008359586,0.0001994502,0.0001421373,0.000236168,0.0001171696,0.0001425675,0.0001292641,0.0001324239,0.0009541502],"category_scores_gemma":[0.00007928315,0.00007210147,0.0001372905,0.0001651064,0.0001301837,0.0001064856,0.0001156563,0.0003267182,0.0002428794],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002032701,"about_ca_system_score_gemma":0.0002240046,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000770642,"about_ca_topic_score_gemma":0.00183051,"domain_scores_codex":[0.999925,0.00001984362,0.000007830298,0.00001177612,0.00002314366,0.00001235577],"domain_scores_gemma":[0.9999598,0.00000828096,0.00001003644,0.00000874698,0.000005282073,0.000007895344],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001472716,0.00002155545,0.0001859596,0.00004773142,0.000005511266,0.00004801013,0.000009838913,0.0001379754,0.9947163,0.0001067491,0.00004602116,0.004527156],"study_design_scores_gemma":[0.000015157,0.0003469059,0.00142615,0.000005809452,0.00001171634,0.0002495345,0.00001215129,0.0002668703,0.9937752,0.00003340939,0.0038549,0.000002136948],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9792972,0.009414911,0.004683365,0.0002330627,0.00003255427,0.00004485148,0.0004772808,0.0001287651,0.005687977],"genre_scores_gemma":[0.9912082,0.003919892,0.002577876,0.00003073939,0.000005025811,0.00001627754,0.0002787611,0.000009375663,0.001953834],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009541502,"threshold_uncertainty_score":0.003191948,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03169583968621449,"score_gpt":0.2775752157047022,"score_spread":0.2458793760184877,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}