{"id":"W2241554143","doi":"10.1080/15384101.2015.1078031","title":"The crucial role of Activin A on the formation of primordial germ cell-like cells from skin-derived stem cells in vitro","year":2015,"lang":"en","type":"article","venue":"Cell Cycle","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"","keywords":"Biology; Embryoid body; Cell biology; Embryonic stem cell; Stem cell; Cellular differentiation; Homeobox protein NANOG; Folliculogenesis; In vitro; LIN28; Molecular biology; Immunology; SOX2; Adult stem cell; Embryogenesis; Genetics; Induced pluripotent stem cell; Embryo","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004937339,0.0001540859,0.0001919895,0.00004390938,0.00006974404,0.00002564625,0.0004843976,0.0001450313,0.000008024608],"category_scores_gemma":[0.00001625737,0.0001053156,0.0001147737,0.000108704,0.0001042102,0.000009162862,0.0002199415,0.0001663534,0.0000307915],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004150096,"about_ca_system_score_gemma":0.0001470006,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002463119,"about_ca_topic_score_gemma":0.00007117552,"domain_scores_codex":[0.998449,0.0002966994,0.0003398813,0.0002497645,0.0003657285,0.0002989255],"domain_scores_gemma":[0.9989043,0.0001366317,0.0002439808,0.0005368946,0.00009759671,0.00008056204],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005732928,0.0001611319,0.0000244664,0.00001792584,0.00001035794,0.000001042395,0.0004957311,0.0003248383,0.9958513,0.000002577003,0.0006538153,0.001883499],"study_design_scores_gemma":[0.0007808409,0.0001662468,0.0001327496,0.000009412747,0.000008185284,2.80552e-7,0.001016201,0.001224819,0.9923555,0.00006733156,0.004130231,0.0001082447],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9943236,0.0003590912,0.00009512799,0.0000567313,0.0001706426,0.0004469891,0.00006670559,0.000004367723,0.00447674],"genre_scores_gemma":[0.999265,0.0001255851,0.00006097005,0.00003579499,0.0001036676,0.00002629478,0.00002907319,0.00002167696,0.0003319292],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004941403,"threshold_uncertainty_score":0.4294647,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0115573641513764,"score_gpt":0.2251683090430455,"score_spread":0.2136109448916691,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}