{"id":"W2245716453","doi":"10.1200/jco.2005.23.16_suppl.3662","title":"A phase II study of neoadjuvant irinotecan (CPT-11), 5-fluorouracil (5-FU) and leucovorin (LV) for resectable liver metastases from colorectal cancer","year":2005,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Hepatocellular Carcinoma Treatment and Prognosis","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Medicine; Metastasectomy; Irinotecan; Colorectal cancer; Chemotherapy; Perioperative; Regimen; Internal medicine; Neoadjuvant therapy; Surgery; Progressive disease; Chemotherapy regimen; Fluorouracil; Clinical endpoint; Phases of clinical research; Gastroenterology; Oncology; Cancer; Clinical trial; Breast cancer","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002797816,0.002090265,0.002372102,0.0005780871,0.000542976,0.0009352981,0.001103222,0.001513644,0.002939616],"category_scores_gemma":[0.001472574,0.0008805232,0.001109655,0.0005924993,0.001442621,0.0008938714,0.0003535771,0.003450656,0.0008703766],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009768783,"about_ca_system_score_gemma":0.002857639,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001109831,"about_ca_topic_score_gemma":0.002974428,"domain_scores_codex":[0.9991552,0.0005016801,0.00003934803,0.0001022955,0.00006859139,0.0001329377],"domain_scores_gemma":[0.9986902,0.0002376452,0.0001891313,0.0001092476,0.00006701671,0.0007066691],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.7020919,0.183523,0.006190392,0.00111923,0.0009851684,0.0005640452,0.0004307918,0.002198517,0.04702735,0.000302632,0.002927968,0.05263901],"study_design_scores_gemma":[0.5627247,0.4285313,0.004186098,0.00002308845,0.0001964139,0.0002368638,0.00004213001,0.0005558784,0.002175932,0.00007449481,0.001235529,0.0000174774],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9913568,0.001463979,0.0005740214,0.0004229375,0.0002146956,0.004399322,0.000507017,0.00005355042,0.001007557],"genre_scores_gemma":[0.9774998,0.002827386,0.003261453,0.001099131,0.0004135326,0.008696831,0.003015822,0.00003273059,0.003153221],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002939616,"threshold_uncertainty_score":0.01479644,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2709697348091951,"score_gpt":0.4643169053032321,"score_spread":0.1933471704940369,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}