{"id":"W2247083811","doi":"10.1200/jco.2007.25.18_suppl.4032","title":"RTOG 0315: A randomized, double-blind, placebo-controlled phase III study to determine the efficacy of octreotide acetate in preventing or reducing the severity of chemoradiation-induced diarrhea in patients with anal or rectal cancer","year":2007,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Colorectal and Anal Carcinomas","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hôpital Notre-Dame","funders":"","keywords":"Medicine; Placebo; Octreotide; Clinical endpoint; Diarrhea; Internal medicine; Gastroenterology; Surgery; Randomized controlled trial; Somatostatin","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002365813,0.001582697,0.003805466,0.0004778258,0.0005363696,0.001099146,0.001369208,0.002505954,0.007360946],"category_scores_gemma":[0.00176996,0.000838497,0.001597206,0.0005865428,0.001301276,0.000869049,0.0003583288,0.002617611,0.001372928],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007548274,"about_ca_system_score_gemma":0.002824562,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001039309,"about_ca_topic_score_gemma":0.002693546,"domain_scores_codex":[0.9991537,0.0004779486,0.00008166013,0.0001067708,0.00005489496,0.0001249131],"domain_scores_gemma":[0.9988059,0.0002832848,0.0002694158,0.00007653786,0.00008230405,0.0004825468],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9599243,0.01957095,0.000682419,0.0007365734,0.0005360934,0.00004436632,0.00005235268,0.0001982844,0.004323914,0.00008836221,0.0009033077,0.01293902],"study_design_scores_gemma":[0.9223064,0.0760861,0.0007281289,0.00001792782,0.0001280628,0.00001932516,0.000008619919,0.0001713128,0.0002037247,0.00003347691,0.0002902247,0.000006629442],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9764264,0.00357018,0.001082227,0.0008067372,0.0006328982,0.01299742,0.001868682,0.0003984652,0.002216963],"genre_scores_gemma":[0.9590799,0.002889375,0.004317913,0.003482806,0.0006370167,0.02376032,0.001851076,0.00004944449,0.003932063],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007360946,"threshold_uncertainty_score":0.02462476,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0927251574017431,"score_gpt":0.4431802084459262,"score_spread":0.3504550510441831,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}