{"id":"W2247744690","doi":"","title":"A monoclonal antibody targeting melanoma-associated chondroitin sulfate proteoglycan demonstrates antitumor activity in human melanoma, ovarian and breast cancer models.","year":2007,"lang":"en","type":"article","venue":"Molecular Cancer Therapeutics","topic":"Glycosylation and Glycoproteins Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Arius3D (Canada)","funders":"","keywords":"Ovarian cancer; Melanoma; Cancer research; Breast cancer; Chondroitin sulfate proteoglycan; Cancer; Medicine; Metastasis; Immunology; Chondroitin sulfate; Internal medicine; Glycosaminoglycan","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000175657,0.0004511526,0.000296518,0.000304604,0.00009378578,0.0001286966,0.0001802965,0.0003507982,0.001495842],"category_scores_gemma":[0.00005977701,0.0001469869,0.0002681904,0.0002164726,0.0000979547,0.0001162331,0.0001201441,0.0007268951,0.0003747538],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000206501,"about_ca_system_score_gemma":0.0001890196,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001077318,"about_ca_topic_score_gemma":0.002139222,"domain_scores_codex":[0.9998857,0.0000182962,0.00000619053,0.00002171623,0.00003528838,0.00003282263],"domain_scores_gemma":[0.9999522,0.000006648711,0.00000990812,0.00000496325,0.00001076481,0.00001553533],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001123721,0.0001334026,0.00008945877,0.00005298937,0.0000116597,0.0000155104,0.00000712777,0.00003698052,0.9960091,0.00004911257,0.0002125376,0.003269719],"study_design_scores_gemma":[0.0001192725,0.004255749,0.006325008,0.00001373672,0.00005600975,0.0004565092,0.00001338134,0.0008555643,0.981126,0.00003750658,0.006734109,0.000007056362],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9745651,0.008189435,0.007907312,0.0003179246,0.0001514139,0.0001856382,0.0009462541,0.000353172,0.007383824],"genre_scores_gemma":[0.9777739,0.004122985,0.006397526,0.0001354778,0.00002947243,0.0001679581,0.002152834,0.00002204551,0.009197717],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001495842,"threshold_uncertainty_score":0.005004048,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01972903891748575,"score_gpt":0.3157827637600911,"score_spread":0.2960537248426053,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}