{"id":"W2251029942","doi":"10.1002/path.4689","title":"Divergent impact of Toll‐like receptor 2 deficiency on repair mechanisms in healthy muscle versus Duchenne muscular dystrophy","year":2016,"lang":"en","type":"article","venue":"The Journal of Pathology","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research","keywords":"Innate immune system; Duchenne muscular dystrophy; Skeletal muscle; Inflammation; TLR2; Macrophage; Macrophage polarization; Biology; Medicine; Immunology; Pathology; Immune system; Endocrinology; Internal medicine; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002783171,0.0004561326,0.0005661206,0.0005232822,0.0001468263,0.0003376112,0.0001964737,0.0005505846,0.001502351],"category_scores_gemma":[0.0002650273,0.0002381379,0.0002399654,0.0001460902,0.0004531943,0.0002364158,0.000303706,0.0004579653,0.0001980975],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002621976,"about_ca_system_score_gemma":0.0001523594,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000315084,"about_ca_topic_score_gemma":0.0006000423,"domain_scores_codex":[0.9996488,0.00006326321,0.00007122411,0.00009559376,0.00005941017,0.00006159379],"domain_scores_gemma":[0.9995571,0.00005866472,0.0001139831,0.00002837449,0.00002124825,0.0002206599],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001142951,0.00009994105,0.00214604,0.00006308201,0.00001338536,0.0002881676,0.0000375342,0.00003728624,0.995,0.00004120997,0.00001924733,0.001111252],"study_design_scores_gemma":[0.0004327921,0.007394223,0.4051866,0.00009615214,0.000183048,0.006348297,0.0005942544,0.001340356,0.5761418,0.0002729089,0.001968502,0.00004111904],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9990977,0.0003884378,0.0001283785,0.00002100617,0.000005565757,0.000006877553,0.0001071773,0.00001011177,0.000234769],"genre_scores_gemma":[0.9978339,0.0003357113,0.0004064115,0.00006421998,0.000006091895,0.00003724985,0.0002741274,0.0000105133,0.00103174],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001502351,"threshold_uncertainty_score":0.005025923,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01273847561565552,"score_gpt":0.2726083887837342,"score_spread":0.2598699131680787,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}