{"id":"W2252525796","doi":"10.1096/fasebj.28.1_supplement.1176.3","title":"Ca <sup>2+</sup> entry via transient receptor potential vanilloid channel 4 mediates ventilation‐induced lung vascular barrier failure (1176.3)","year":2014,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Chronic Obstructive Pulmonary Disease (COPD) Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Michael's Hospital","funders":"Deutsche Forschungsgemeinschaft","keywords":"Transient receptor potential channel; Mechanosensitive channels; SGK1; TRPV4; In vivo; Chemistry; TRPC; Charybdotoxin; Ex vivo; Lung; Internal medicine; Medicine; Receptor; Biology; Kinase; Ion channel; Potassium channel; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003879289,0.0004340864,0.0006045841,0.0002367485,0.0001946442,0.0004102824,0.0004361207,0.0006364932,0.00292245],"category_scores_gemma":[0.0003095767,0.0001969676,0.0006679129,0.0001262131,0.0004934128,0.000374474,0.0003407084,0.000997104,0.00070596],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003125955,"about_ca_system_score_gemma":0.0002371943,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002809814,"about_ca_topic_score_gemma":0.0002432561,"domain_scores_codex":[0.9997783,0.00004154766,0.00002392065,0.00002811403,0.00004703048,0.00008097701],"domain_scores_gemma":[0.9998203,0.00002199078,0.00006895657,0.00001492662,0.00001525204,0.00005852971],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001014362,0.00005073295,0.0008322361,0.0001037671,0.00001545966,0.0004140231,0.00001451166,0.0001087091,0.9960626,0.000126303,0.000155211,0.001102143],"study_design_scores_gemma":[0.0002938263,0.002394462,0.03063773,0.00004094811,0.000124443,0.00360937,0.0001653596,0.005253552,0.9544687,0.000405542,0.002585286,0.00002069906],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9934249,0.001294255,0.003461048,0.0003302979,0.00007084144,0.00004405706,0.000282941,0.0001255487,0.0009661486],"genre_scores_gemma":[0.9967802,0.0004706244,0.0009218862,0.0001363344,0.00003337457,0.0000594805,0.0003037511,0.00001664967,0.001277573],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00292245,"threshold_uncertainty_score":0.009776533,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008399531325238626,"score_gpt":0.2400998483917091,"score_spread":0.2317003170664705,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}