{"id":"W2252620266","doi":"10.1016/j.jid.2015.12.033","title":"The Expression of IL-21 Is Promoted by MEKK4 in Malignant T Cells and Associated with Increased Progression Risk in Cutaneous T-Cell Lymphoma","year":2016,"lang":"en","type":"letter","venue":"Journal of Investigative Dermatology","topic":"Cutaneous lymphoproliferative disorders research","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University Health Centre; Ottawa Hospital; University of Ottawa","funders":"Novo Nordisk Fonden","keywords":"Cytotoxic T cell; CD8; Cancer research; T cell; Medicine; Lymphoma; Immunology; Cytokine; Interleukin 15; Interleukin; Interleukin 3; Cancer; Interleukin 21; Biology; Immune system; Internal medicine; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001783958,0.0002187437,0.0003512792,0.0002552655,0.0003833981,0.0005084216,0.0002675216,0.001069635,0.001695724],"category_scores_gemma":[0.001312257,0.0001361061,0.000294136,0.0002457956,0.0002580344,0.0003459758,0.0001854,0.0011789,0.0005894739],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000315436,"about_ca_system_score_gemma":0.0001401148,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003258236,"about_ca_topic_score_gemma":0.0004454432,"domain_scores_codex":[0.9997838,0.00005663109,0.00002785507,0.0000306996,0.00004794467,0.00005310439],"domain_scores_gemma":[0.9994868,0.0001979778,0.00008562786,0.00005706102,0.00009243079,0.00008000614],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00507363,0.0004117692,0.4555539,0.0004687906,0.0001839278,0.3791391,0.0006475543,0.0006191253,0.07488947,0.00243836,0.02368375,0.05689057],"study_design_scores_gemma":[0.000411534,0.0008534614,0.448839,0.0001122603,0.0003095723,0.4640515,0.0008032552,0.005327084,0.02038278,0.004194935,0.05463302,0.00008152151],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9680884,0.002751772,0.0008294198,0.01679341,0.001136066,0.00003507615,0.0002801328,0.0001070243,0.00997879],"genre_scores_gemma":[0.9936207,0.0005605179,0.0003366968,0.001878705,0.001276691,0.00001243491,0.00007428968,0.00001041245,0.002229543],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001695724,"threshold_uncertainty_score":0.005672753,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01088932298702803,"score_gpt":0.2578453042270177,"score_spread":0.2469559812399897,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}