{"id":"W2253212012","doi":"10.1186/s13104-015-1780-x","title":"EV71 virus-like particles produced by co-expression of capsid proteins in yeast cells elicit humoral protective response against EV71 lethal challenge","year":2016,"lang":"en","type":"article","venue":"BMC Research Notes","topic":"Viral Infections and Immunology Research","field":"Medicine","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"National Natural Science Foundation of China; National High-tech Research and Development Program; Deutsche Forschungsgemeinschaft","keywords":"Capsid; Enterovirus 71; Virology; Virus-like particle; Immunization; Virus; Biology; Antibody; Recombinant DNA; Immune system; In vitro; Microbiology; Immunology; Enterovirus; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001352271,0.0004029,0.0002063833,0.0001635508,0.0001058148,0.0002788818,0.0002211415,0.0002542495,0.000822317],"category_scores_gemma":[0.0001253244,0.0001168206,0.0002763465,0.0001721029,0.0001704377,0.0001646823,0.0002665259,0.0006704106,0.0004251346],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002454612,"about_ca_system_score_gemma":0.0001580781,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003730496,"about_ca_topic_score_gemma":0.0003310734,"domain_scores_codex":[0.9998925,0.00002047124,0.00001372561,0.0000198324,0.00002786484,0.00002557427],"domain_scores_gemma":[0.9999232,0.00001323755,0.00002398086,0.00001251799,0.00001229114,0.0000147496],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008439475,0.0000319704,0.0002179272,0.0000374177,0.000006973318,0.00004101622,0.00001282289,0.00009391893,0.9986958,0.00008205078,0.00004940838,0.0006463061],"study_design_scores_gemma":[0.00001763555,0.0003039674,0.001612719,0.000009286847,0.00002541954,0.0002163318,0.00003244868,0.0006918926,0.9949914,0.0000477193,0.002047333,0.000003826965],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9917121,0.0006827122,0.0057763,0.0001059481,0.00004765715,0.00003675722,0.0004575938,0.0001034582,0.001077521],"genre_scores_gemma":[0.989578,0.0005521449,0.00590158,0.0000408035,0.00001214013,0.00004197279,0.001515264,0.0000395446,0.002318632],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000822317,"threshold_uncertainty_score":0.002750874,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1396770526975499,"score_gpt":0.4132728935751653,"score_spread":0.2735958408776155,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}