{"id":"W2253717179","doi":"10.1039/c5tx00358j","title":"The influence of the SULT1A status – wild-type, knockout or humanized – on the DNA adduct formation by methyleugenol in extrahepatic tissues of mice","year":2016,"lang":"en","type":"article","venue":"Toxicology Research","topic":"Carcinogens and Genotoxicity Assessment","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"Nutrasource","funders":"","keywords":"Adduct; Sulfotransferase; DNA adduct; Chemistry; Kidney; Caecum; Carcinogen; Knockout mouse; Spleen; Internal medicine; Endocrinology; Biochemistry; Enzyme; Molecular biology; Biology; Medicine; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001533474,0.0001053729,0.000160175,0.00005562222,0.0002042684,0.00001286436,0.0005538642,0.000136731,0.0000501847],"category_scores_gemma":[0.001035626,0.00004338952,0.00005329918,0.0002912401,0.0005930437,0.000006586985,0.0002612148,0.0001867301,0.000007862098],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005870403,"about_ca_system_score_gemma":0.0002367651,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001411108,"about_ca_topic_score_gemma":0.001530768,"domain_scores_codex":[0.9978542,0.0008760476,0.00031731,0.0002116074,0.0003374609,0.0004033269],"domain_scores_gemma":[0.9982967,0.0006678637,0.0001300785,0.0005689827,0.0002981404,0.00003817823],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004610581,0.00008651288,0.001123735,0.00001646063,0.00003789986,7.129908e-7,0.0002201686,0.0000123355,0.9930102,0.0003279905,0.002080956,0.002621962],"study_design_scores_gemma":[0.0005560228,0.0009257789,0.01728059,0.00003336416,0.000008646377,0.000003301193,0.0003102213,0.00001375853,0.9669463,0.0002152248,0.01363828,0.00006849317],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965858,0.000614012,0.00001146752,0.00181333,0.00004259993,0.0006611184,0.00004100857,0.000002442403,0.000228165],"genre_scores_gemma":[0.9973092,0.0009697306,0.00002054245,0.00009450394,0.00002405228,0.00007357807,0.000006284701,0.00001077054,0.001491321],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02606389,"threshold_uncertainty_score":0.2185094,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04727238433317336,"score_gpt":0.3656507235886557,"score_spread":0.3183783392554823,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}