{"id":"W2254080944","doi":"10.1161/hyp.62.suppl_1.a350","title":"Abstract 350: Downregulation of C-terminal Src Kinase (csk) and Csk-binding Protein (cbp) is Associated With Increased Aldosterone-induced C-src Phosphorylation in Shr Vascular Smooth Muscle Cells","year":2013,"lang":"en","type":"article","venue":"Hypertension","topic":"Hormonal Regulation and Hypertension","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"","keywords":"Proto-oncogene tyrosine-protein kinase Src; Phosphorylation; Aldosterone; Tyrosine-protein kinase CSK; Cell biology; Kinase; Vascular smooth muscle; Biology; Src family kinase; Chemistry; Endocrinology; Internal medicine; SH3 domain; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001360118,0.0004061737,0.0005104036,0.0002297791,0.0002041928,0.0002416882,0.000170723,0.0003027115,0.003578886],"category_scores_gemma":[0.0001001604,0.0001857648,0.00035038,0.0001411476,0.0002749415,0.0002053105,0.0002158323,0.0009856889,0.0006773379],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002624927,"about_ca_system_score_gemma":0.000190268,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00103371,"about_ca_topic_score_gemma":0.0008243129,"domain_scores_codex":[0.9997609,0.00002805336,0.00002879209,0.00004541046,0.00007252281,0.00006424185],"domain_scores_gemma":[0.9998143,0.00001818414,0.00004127932,0.00001654613,0.00002290596,0.00008678777],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001043853,0.00002219985,0.00009334639,0.00002682882,0.000004091666,0.00004732555,0.000008004471,0.00000643362,0.9993008,0.00002042797,0.00004269297,0.0003234654],"study_design_scores_gemma":[0.00005326834,0.0007504182,0.02333684,0.000009733487,0.00003411945,0.0005023609,0.0000562754,0.0006708166,0.9727611,0.0000495775,0.001767709,0.000007887245],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9956614,0.001352305,0.0009541294,0.0001590169,0.00005985278,0.00001980603,0.0006437868,0.00009937157,0.001050254],"genre_scores_gemma":[0.9900767,0.001009899,0.001383141,0.0001818605,0.00007122676,0.00007874436,0.001439158,0.00003383266,0.005725617],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003578886,"threshold_uncertainty_score":0.01197255,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02238600051809305,"score_gpt":0.2237830468330549,"score_spread":0.2013970463149618,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}