{"id":"W2255070194","doi":"10.1021/acs.jpcb.5b10381","title":"DNA Distortion Caused by Uracil-Containing Intrastrand Cross-Links","year":2016,"lang":"en","type":"article","venue":"The Journal of Physical Chemistry B","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Lethbridge","funders":"Natural Sciences and Engineering Research Council of Canada; Göteborgs Universitet; University of Lethbridge; Canada Research Chairs; Canada Foundation for Innovation; Alberta Innovates - Technology Futures","keywords":"Uracil; DNA; Chemistry; Distortion (music); Computational biology; Biophysics; Computer science; Biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000755837,0.0002237374,0.0001483349,0.0002386611,0.0001877691,0.0002029548,0.0002084688,0.0003089422,0.001054235],"category_scores_gemma":[0.0003109672,0.0001749044,0.0001985515,0.0002925907,0.0002170294,0.0002329754,0.0002448031,0.0002636075,0.0001803871],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001859577,"about_ca_system_score_gemma":0.0001002548,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009475987,"about_ca_topic_score_gemma":0.000985235,"domain_scores_codex":[0.9999107,0.00001186082,0.000005094306,0.00002263476,0.00003408084,0.00001554936],"domain_scores_gemma":[0.9998096,0.00004343137,0.00007771826,0.00002007181,0.00002393527,0.00002526381],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002394958,0.00002892034,0.005376493,0.0001397373,0.00005542565,0.0004480376,0.0001729911,0.005384515,0.9834309,0.0002950918,0.00006664525,0.004361772],"study_design_scores_gemma":[0.00002037101,0.0003316684,0.04073251,0.00001702925,0.00006661769,0.001709295,0.0001569132,0.01248909,0.9419695,0.0003573218,0.00211427,0.0000354308],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969077,0.0008914728,0.001342224,0.00001899795,0.00000781678,0.000007195972,0.00008898495,0.00002856822,0.000707062],"genre_scores_gemma":[0.9988351,0.0002948146,0.0004822681,0.00000861537,0.000001175582,0.000002709773,0.0001034113,0.000004548605,0.0002673059],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001054235,"threshold_uncertainty_score":0.003526747,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006255538950379198,"score_gpt":0.2474894416603939,"score_spread":0.2412339027100147,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}