{"id":"W2255224851","doi":"10.1371/journal.pgen.1005651","title":"Connecting Replication and Repair: YoaA, a Helicase-Related Protein, Promotes Azidothymidine Tolerance through Association with Chi, an Accessory Clamp Loader Protein","year":2015,"lang":"en","type":"article","venue":"PLoS Genetics","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institute of Genetics; National Institute of General Medical Sciences","keywords":"Biology; Helicase; DNA replication; Genetics; Replication factor C; Control of chromosome duplication; DNA repair; RNA Helicase A; Proofreading; Minichromosome maintenance; Replication protein A; Cell biology; DNA polymerase; DNA; Gene; DNA-binding protein; RNA","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005490248,0.0002576383,0.0002250417,0.00003237,0.0001248737,0.00007110611,0.0001858281,0.0003250265,0.000006969843],"category_scores_gemma":[0.000471568,0.0002426871,0.00004967579,0.0001635304,0.00004161745,0.00002767276,0.0001192834,0.0001778038,0.000007118832],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006837634,"about_ca_system_score_gemma":0.0001164752,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001230648,"about_ca_topic_score_gemma":0.00004993209,"domain_scores_codex":[0.9979297,0.0002067925,0.0003526947,0.0008297069,0.0003458382,0.0003352838],"domain_scores_gemma":[0.9982368,0.000008726063,0.0003562479,0.0008495871,0.0003971141,0.0001515215],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001068732,0.0002071383,0.002014008,0.00006817971,0.0001249103,0.000003881186,0.0004912213,0.0000937373,0.9962969,0.00008572456,0.00004755375,0.0004598099],"study_design_scores_gemma":[0.001030097,0.001398724,0.0001473109,0.00008611106,0.00006039882,0.00002781938,0.00017183,0.006338959,0.9885004,0.000556042,0.001328035,0.0003542334],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9957476,0.0009865777,0.0007662436,0.0002683637,0.00003587148,0.001699307,0.00001597829,0.0001919706,0.0002880509],"genre_scores_gemma":[0.9781572,0.00002847023,0.02049442,0.0001233536,0.0001797706,0.0003111338,0.0001376241,0.00007485134,0.0004932052],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01972817,"threshold_uncertainty_score":0.9896491,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02726315393519617,"score_gpt":0.262059412019594,"score_spread":0.2347962580843979,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}