{"id":"W2255403518","doi":"10.1038/ncomms10147","title":"Local admixture of amplified and diversified secreted pathogenesis determinants shapes mosaic Toxoplasma gondii genomes","year":2016,"lang":"en","type":"article","venue":"Nature Communications","topic":"Toxoplasma gondii Research Studies","field":"Immunology and Microbiology","cited_by":275,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; U.S. Public Health Service; National Institutes of Health; U.S. Department of Health and Human Services","keywords":"Biology; Genome; Toxoplasma gondii; Genetics; Pathogenesis; Population; Gene; Virology; Evolutionary biology; Immunology; Antibody","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002306046,0.0002050196,0.0003707559,0.0001860762,0.0004653602,0.00001065041,0.001009458,0.0006219067,0.00008797644],"category_scores_gemma":[0.0004111179,0.0001464251,0.00009197907,0.0002407734,0.00122868,0.0001120678,0.001178372,0.0005797513,0.000068033],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005506283,"about_ca_system_score_gemma":0.00008355818,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002655477,"about_ca_topic_score_gemma":0.0006363983,"domain_scores_codex":[0.9986039,0.0003609816,0.0003032129,0.000307121,0.00007059711,0.0003542228],"domain_scores_gemma":[0.9974173,0.001074307,0.0001683406,0.001054747,0.0002358327,0.00004943614],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0003311879,0.0002333082,0.06452411,0.00006601431,0.0006468573,0.000006343949,0.001153915,6.221899e-7,0.8357525,0.006603425,0.005215428,0.08546633],"study_design_scores_gemma":[0.005068133,0.0005371854,0.4524576,0.0003143376,0.0003229048,0.0001683178,0.001895117,0.00004596411,0.2238848,0.000701037,0.3136602,0.0009444402],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9183546,0.07525399,0.0002968672,0.002784868,0.000222639,0.0006270872,0.001546102,0.0001478706,0.0007660171],"genre_scores_gemma":[0.9914141,0.006769527,0.0006880797,0.00008497938,0.000008130919,0.00005230213,0.00009265319,0.0000184606,0.000871795],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6118677,"threshold_uncertainty_score":0.5971044,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02211709811630552,"score_gpt":0.2856563367906474,"score_spread":0.2635392386743419,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}