{"id":"W2255593359","doi":"10.1200/jco.2007.25.18_suppl.4068","title":"Phase IV study of first-line bevacizumab plus irinotecan and infusional 5-FU/LV in patients with metastatic colorectal cancer: AVIRI","year":2007,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Colorectal Cancer Treatments and Studies","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"International Development Research Centre","funders":"","keywords":"Medicine; Irinotecan; Bevacizumab; FOLFIRI; Regimen; Colorectal cancer; Internal medicine; Oncology; Phases of clinical research; Fluorouracil; Surgery; Chemotherapy; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001715082,0.001305995,0.002426073,0.0005238346,0.000362541,0.0009334729,0.001297926,0.001483543,0.00386325],"category_scores_gemma":[0.00102348,0.0006039554,0.001123296,0.0004135892,0.0006614352,0.0005599502,0.0004004738,0.002977656,0.001195155],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00117359,"about_ca_system_score_gemma":0.002160566,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001867688,"about_ca_topic_score_gemma":0.003568335,"domain_scores_codex":[0.9994873,0.0002356937,0.0000176706,0.00007785513,0.00004701392,0.0001344826],"domain_scores_gemma":[0.9990674,0.0001217528,0.0001137096,0.00007921072,0.00008690068,0.0005310149],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.6591615,0.1354117,0.007530013,0.0009552645,0.001525854,0.0003730148,0.0004135238,0.002517486,0.07192844,0.0003176066,0.005045608,0.1148201],"study_design_scores_gemma":[0.5577646,0.4235925,0.01071847,0.00002939756,0.0003225679,0.0002917537,0.00003519814,0.001207405,0.002801626,0.00007857426,0.003135294,0.0000225902],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9902651,0.002418466,0.0006299549,0.0005214021,0.000156369,0.002905197,0.0008886194,0.0001353601,0.002079479],"genre_scores_gemma":[0.983976,0.00168867,0.002397287,0.001037413,0.0003761156,0.003345885,0.003660606,0.00004752772,0.003470507],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00386325,"threshold_uncertainty_score":0.01292384,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08033455945256691,"score_gpt":0.4617992252682193,"score_spread":0.3814646658156524,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}