{"id":"W2256374136","doi":"10.1136/annrheumdis-2015-eular.2907","title":"THU0420 Long-Term (104-Week) Efficacy and Safety Profile of Apremilast, An Oral Phosphodiesterase 4 Inhibitor, in Patients with Psoriatic Arthritis: Results from a Phase III, Randomised, Controlled Trial and Open-Label Extension (Palace 1)","year":2015,"lang":"en","type":"article","venue":"Annals of the Rheumatic Diseases","topic":"Rheumatoid Arthritis Research and Therapies","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":false,"ca_institutions":"Toronto Western Hospital","funders":"","keywords":"Medicine; Apremilast; Psoriatic arthritis; Randomized controlled trial; Internal medicine; Placebo; Psoriasis; Rheumatology; Gastroenterology; Rheumatoid arthritis; Dermatology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002263199,0.001493544,0.00290023,0.0005563211,0.0004080544,0.001019274,0.001215711,0.001977981,0.006741048],"category_scores_gemma":[0.00159611,0.0008120652,0.002452003,0.0004536318,0.001246594,0.001654253,0.0003866645,0.004198779,0.001462963],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005526238,"about_ca_system_score_gemma":0.0009465294,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006283988,"about_ca_topic_score_gemma":0.001376748,"domain_scores_codex":[0.9992515,0.0003752691,0.00004870529,0.0001166306,0.00008114564,0.0001267388],"domain_scores_gemma":[0.9990684,0.0002321962,0.0002114773,0.00009191778,0.00006558614,0.0003302963],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8923529,0.01646878,0.001260412,0.001010961,0.00132029,0.0001141863,0.0001071871,0.0008897308,0.01858221,0.0001322459,0.001834854,0.06592634],"study_design_scores_gemma":[0.7622993,0.2268516,0.00637534,0.0000398178,0.0006581229,0.0001772118,0.00003599699,0.0006085005,0.001880658,0.0001094794,0.0009246508,0.00003941089],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9860423,0.006616824,0.0008145685,0.0006824202,0.0002756248,0.001154222,0.002070091,0.0002780264,0.00206584],"genre_scores_gemma":[0.9844548,0.003473385,0.002213211,0.001198072,0.0004896027,0.001641372,0.002847502,0.00006555318,0.003616408],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006741048,"threshold_uncertainty_score":0.02255106,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05224593430081605,"score_gpt":0.3339230729321379,"score_spread":0.2816771386313218,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}