{"id":"W2256952914","doi":"10.1161/res.113.suppl_1.a308","title":"Abstract 308: Controlling Methylglyoxal To Prevent The Development Of Diabetic Cardiomyopathy","year":2013,"lang":"en","type":"article","venue":"Circulation Research","topic":"Advanced Glycation End Products research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"","keywords":"Methylglyoxal; Diabetic cardiomyopathy; Diabetes mellitus; Internal medicine; Glycation; Endocrinology; Medicine; Streptozotocin; Lactoylglutathione lyase; Ejection fraction; Cardiomyopathy; Intraperitoneal injection; Heart failure; Chemistry; Biochemistry; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00196848,0.00008960813,0.0001195468,0.0001289135,0.0002141933,0.00004327906,0.0003204852,0.00006787449,0.0001372281],"category_scores_gemma":[0.0009866414,0.00006944842,0.0000504232,0.0003546668,0.0001008909,0.000009504528,0.000167967,0.0001825414,0.0001595362],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005284604,"about_ca_system_score_gemma":0.0002778962,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003313209,"about_ca_topic_score_gemma":0.00001143943,"domain_scores_codex":[0.998131,0.0002365216,0.0003134982,0.0003235288,0.0006418477,0.0003536496],"domain_scores_gemma":[0.9981638,0.0001172473,0.00005400225,0.0005122713,0.00103597,0.000116681],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002287198,0.00005805578,0.00189762,0.00003858922,0.00004976679,2.245622e-7,0.0004003729,0.009289343,0.9463809,0.0001083403,0.0003799441,0.04137403],"study_design_scores_gemma":[0.0004544244,0.00009540693,0.3135601,0.00003284643,0.000005470985,0.000001734531,0.0004607283,0.0006124804,0.6694559,0.001215254,0.01388268,0.0002228601],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.986751,0.0004883371,0.009150183,0.0009049349,0.00005327573,0.001161973,0.000003049743,0.000006934399,0.001480315],"genre_scores_gemma":[0.997304,0.00001435895,0.001787439,0.00003238165,0.0001389534,0.0003105294,0.00003292381,0.0000174946,0.0003618994],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3116625,"threshold_uncertainty_score":0.2832024,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05303744630115595,"score_gpt":0.3705337631748868,"score_spread":0.3174963168737308,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}