{"id":"W2257172488","doi":"10.1210/en.2015-1862","title":"All Hormone-Producing Cell Types of the Pituitary Intermediate and Anterior Lobes Derive From Prop1-Expressing Progenitors","year":2016,"lang":"en","type":"article","venue":"Endocrinology","topic":"Growth Hormone and Insulin-like Growth Factors","field":"Medicine","cited_by":80,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Child Health and Human Development; National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Cancer Institute; National Institutes of Health; National Institute of Diabetes and Digestive and Kidney Diseases; McGill University; Directorate for Biological Sciences; University of South Carolina; Eunice Kennedy Shriver National Institute of Child Health and Human Development; U.S. Public Health Service; University of Michigan","keywords":"Anterior pituitary; Internal medicine; Endocrinology; Biology; Somatotropic cell; Pituitary gland; Transgene; Progenitor cell; Stem cell; Hormone; Cell biology; Gene; Medicine; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004981066,0.0001991625,0.0003818278,0.00007391913,0.00006266822,0.000009611839,0.0001739116,0.0000909525,0.00002862387],"category_scores_gemma":[0.0001456854,0.0001061651,0.00009011064,0.00007734531,0.0003912106,0.0001212162,0.0002411215,0.0001849286,0.00002027844],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003275383,"about_ca_system_score_gemma":0.0000554713,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001618663,"about_ca_topic_score_gemma":0.000007966484,"domain_scores_codex":[0.9986745,0.00007939643,0.0003214704,0.0003845306,0.0001432477,0.000396918],"domain_scores_gemma":[0.9991698,0.00009608489,0.0001650779,0.0004077087,0.00006875616,0.00009254661],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002199162,0.00007661002,0.1914042,0.0000479472,0.0001103078,0.00004896834,0.001136843,7.326913e-8,0.7905142,0.00001283715,0.0004937134,0.01593439],"study_design_scores_gemma":[0.001381474,0.0003502907,0.4348305,0.00015199,0.0001240485,0.0000603646,0.0001955055,0.000004545984,0.5606559,0.0001200923,0.001994144,0.0001311524],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9932218,0.004181392,0.00003801331,0.001433555,0.0004352834,0.0003482632,0.00002312094,0.00005174509,0.0002668584],"genre_scores_gemma":[0.9983799,0.0005891688,0.0003400538,0.0002289295,0.0002452108,0.00001956955,0.000004341737,0.00002787613,0.0001649291],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2434263,"threshold_uncertainty_score":0.4329286,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.013397226805148,"score_gpt":0.2368641099102405,"score_spread":0.2234668831050925,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}