{"id":"W2257172488","doi":"10.1210/en.2015-1862","title":"All Hormone-Producing Cell Types of the Pituitary Intermediate and Anterior Lobes Derive From Prop1-Expressing Progenitors","year":2016,"lang":"en","type":"article","venue":"Endocrinology","topic":"Growth Hormone and Insulin-like Growth Factors","field":"Medicine","cited_by":80,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Child Health and Human Development; National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Cancer Institute; National Institutes of Health; National Institute of Diabetes and Digestive and Kidney Diseases; McGill University; Directorate for Biological Sciences; University of South Carolina; Eunice Kennedy Shriver National Institute of Child Health and Human Development; U.S. Public Health Service; University of Michigan","keywords":"Anterior pituitary; Internal medicine; Endocrinology; Biology; Somatotropic cell; Pituitary gland; Transgene; Progenitor cell; Stem cell; Hormone; Cell biology; Gene; Medicine; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001507506,0.0004006562,0.0002098743,0.0004646331,0.0002712524,0.0004153985,0.0002948753,0.000233003,0.002115174],"category_scores_gemma":[0.0001690632,0.0002459766,0.0002699595,0.0001837979,0.0003918927,0.0002816944,0.0004220126,0.0006910971,0.0007071707],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002163604,"about_ca_system_score_gemma":0.0003173623,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005294772,"about_ca_topic_score_gemma":0.001065693,"domain_scores_codex":[0.9998692,0.00000892074,0.00001023286,0.00002770151,0.00004673973,0.00003716911],"domain_scores_gemma":[0.9998229,0.0000326442,0.00004427063,0.00001772192,0.00001560034,0.0000668629],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000107295,0.000008670242,0.0016893,0.00003191069,0.000003771474,0.0003560183,0.0000493866,0.00003149975,0.9947801,0.0003430251,0.00004146867,0.002557575],"study_design_scores_gemma":[0.00003703194,0.000221848,0.03382972,0.0000315243,0.00003064115,0.004250382,0.0001647289,0.0006414835,0.9509381,0.0003373934,0.009500912,0.0000162753],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9873209,0.001130629,0.006293401,0.00009831377,0.00001479103,0.00004502982,0.0006779501,0.00009277841,0.0043262],"genre_scores_gemma":[0.9850756,0.001224976,0.006687247,0.00007163022,0.00001031278,0.00006078135,0.001525173,0.00005443154,0.005289924],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002115174,"threshold_uncertainty_score":0.007075906,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.013397226805148,"score_gpt":0.2368641099102405,"score_spread":0.2234668831050925,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}