{"id":"W2257493522","doi":"10.1161/atvb.34.suppl_1.75","title":"Abstract 75: Characterization of Knock-in Mice Harboring a Variant of Endothelial Protein C Receptor with Impaired Ability to Bind Protein C: Impact on Coagulation and Hematopoiesis","year":2014,"lang":"en","type":"article","venue":"Arteriosclerosis Thrombosis and Vascular Biology","topic":"Blood Coagulation and Thrombosis Mechanisms","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"","keywords":"Endothelial protein C receptor; Protein C; Knockout mouse; Thrombomodulin; Haematopoiesis; Thrombin; Biology; Immunology; Thromboplastin; Molecular biology; Receptor; Coagulation; Cell biology; Stem cell; Medicine; Internal medicine; Platelet; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003919526,0.001420971,0.0006442775,0.00137546,0.0003812783,0.0006916107,0.0007882332,0.001364764,0.006561476],"category_scores_gemma":[0.0002861851,0.0004957455,0.0008847525,0.0003200651,0.0009526491,0.0005657511,0.0004792139,0.001595214,0.00291576],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005735371,"about_ca_system_score_gemma":0.0003391943,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001316106,"about_ca_topic_score_gemma":0.001122613,"domain_scores_codex":[0.9992992,0.00006017834,0.0001018371,0.0002134985,0.0001624617,0.0001628035],"domain_scores_gemma":[0.9992849,0.00009131222,0.0002538687,0.00006394116,0.00004349673,0.0002625175],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002518186,0.0001826827,0.0001907848,0.00003945516,0.00001968296,0.0004785075,0.00003376356,0.00008014261,0.9972523,0.000337906,0.0001454038,0.000987563],"study_design_scores_gemma":[0.0004323736,0.002317233,0.01280088,0.00005661126,0.000180075,0.0056113,0.0001178463,0.002374644,0.9643375,0.0002741203,0.01143933,0.00005808168],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9790832,0.001081947,0.009693949,0.0005855576,0.0001586204,0.0002702368,0.005813727,0.0004474891,0.002865221],"genre_scores_gemma":[0.9509876,0.001537532,0.01246474,0.0005139878,0.0001096,0.0004328598,0.008051388,0.0007191809,0.02518305],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006561476,"threshold_uncertainty_score":0.02195036,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02095375190583176,"score_gpt":0.2639953378910353,"score_spread":0.2430415859852035,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}