{"id":"W2257589245","doi":"10.1096/fj.15-275131","title":"Chaperome screening leads to identification of Grp94/Gp96 and FKBP4/52 as modulators of the α‐synuclein‐elicited immune response","year":2015,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Heat shock proteins research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Medical Research Council; Federación Española de Enfermedades Raras; Wellcome Trust; Wellcome","keywords":"Immune system; Phenotype; Biology; Chaperone (clinical); Antibody; Cell biology; Chemistry; Immunology; Biochemistry; Medicine; Gene","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00251669,0.00009234576,0.000133635,0.00008471123,0.0001475686,0.00003195359,0.0004297044,0.00007864503,0.00001047427],"category_scores_gemma":[0.001101169,0.00005762904,0.00007516277,0.0002154148,0.0001682896,0.00000823705,0.0002641315,0.0001962051,0.000005087411],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001986947,"about_ca_system_score_gemma":0.0001564537,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004772201,"about_ca_topic_score_gemma":0.000003834866,"domain_scores_codex":[0.9984626,0.0004686968,0.0003579277,0.000136233,0.0003803423,0.0001942398],"domain_scores_gemma":[0.9989132,0.00003136525,0.0001627446,0.0004610394,0.0002929037,0.0001387711],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007981096,0.00001989649,0.001430448,0.000005365393,0.00003382261,0.000001582997,0.0004015302,0.0002838128,0.9956243,0.00001890297,0.00009232941,0.001289894],"study_design_scores_gemma":[0.0004055976,0.0003372714,0.02650187,0.00003203721,0.00001211856,0.0001042528,0.0003266647,0.0002192269,0.9715725,0.0000802598,0.0003434211,0.00006483073],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969544,0.0004204973,0.0009138754,0.001364561,0.00005839204,0.0002257997,0.00001074152,0.000002616963,0.00004914247],"genre_scores_gemma":[0.9990914,0.00003428503,0.0001595907,0.00007813831,0.00007502168,0.000005065504,0.000002509365,0.00001636405,0.00053755],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02507142,"threshold_uncertainty_score":0.2350044,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0258243062489519,"score_gpt":0.2998294368949,"score_spread":0.2740051306459482,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}