{"id":"W2258517306","doi":"10.1101/pdb.prot085118","title":"Analysis of Replicating Yeast Chromosomes by DNA Combing","year":2016,"lang":"en","type":"article","venue":"Cold Spring Harbor Protocols","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Combing; DNA; DNA replication; Yeast; Biology; Chemistry; Cell biology; Molecular biology; Genetics; Materials science","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003004711,0.000515111,0.0003498129,0.001931161,0.0004281913,0.0003172395,0.0003275602,0.0003060592,0.001763295],"category_scores_gemma":[0.0002543663,0.0002678843,0.000378101,0.001296383,0.0003183435,0.0003283873,0.0003004493,0.0006694579,0.0006338101],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003175705,"about_ca_system_score_gemma":0.0001760555,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005194152,"about_ca_topic_score_gemma":0.001275211,"domain_scores_codex":[0.9997661,0.00003371947,0.0000228809,0.00007338521,0.00008327212,0.00002068344],"domain_scores_gemma":[0.9998031,0.00006723866,0.00003959571,0.00004181941,0.00002840032,0.00001987988],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002634731,0.00001072978,0.0002797539,0.00004280941,0.000008258244,0.00003935177,0.00002901003,0.00009831522,0.9957419,0.0001495021,0.00002886848,0.00354514],"study_design_scores_gemma":[0.000007354619,0.0001827364,0.006157778,0.00001040861,0.00002905429,0.0002273354,0.00004982855,0.001641406,0.9870197,0.000225934,0.004439452,0.000008934065],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"methods","genre_scores_codex":[0.683528,0.004819249,0.2975429,0.0001758009,0.0001716126,0.000686909,0.003027718,0.001790671,0.008257188],"genre_scores_gemma":[0.6488354,0.004536093,0.3354674,0.0001124203,0.00004182596,0.00109533,0.003267704,0.0002745195,0.006369314],"genre_candidate":"methods","genre_consensus":null,"teacher_disagreement_score":0.001931161,"threshold_uncertainty_score":0.005898774,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01177796719087136,"score_gpt":0.2656573748553598,"score_spread":0.2538794076644885,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}