{"id":"W2258517306","doi":"10.1101/pdb.prot085118","title":"Analysis of Replicating Yeast Chromosomes by DNA Combing","year":2016,"lang":"en","type":"article","venue":"Cold Spring Harbor Protocols","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Combing; DNA; DNA replication; Yeast; Biology; Chemistry; Cell biology; Molecular biology; Genetics; Materials science","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002958477,0.0001384306,0.0002518379,0.00007522973,0.00004651421,0.00001806782,0.0003003538,0.000103557,0.00003558318],"category_scores_gemma":[0.0001596912,0.0001143563,0.0001654995,0.0002338436,0.0000532079,0.000005403134,0.0001694181,0.00004006774,0.000007834289],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002497875,"about_ca_system_score_gemma":0.00003701707,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000009155742,"about_ca_topic_score_gemma":0.000002724961,"domain_scores_codex":[0.9988359,0.00004747269,0.0002976145,0.0004253598,0.0001600574,0.0002335797],"domain_scores_gemma":[0.9988005,0.00001636795,0.0002186635,0.0008105619,0.00007642562,0.0000774877],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002191494,0.00005888873,0.009398836,0.00002858624,0.0002567274,8.027478e-7,0.000004404541,0.000002445865,0.9886759,0.001010047,0.000122242,0.0004191896],"study_design_scores_gemma":[0.0004587751,0.0001448266,0.003311947,0.00009527307,0.00007168108,1.668568e-7,0.000002648423,0.00005916988,0.9797578,0.000006444011,0.01593324,0.0001579955],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.975536,0.00006606742,0.005807231,0.0000721641,0.00002768947,0.01803554,0.00005823005,0.00006593933,0.0003310845],"genre_scores_gemma":[0.975311,0.000004100579,0.001005555,0.0000447418,0.0000415741,0.02327942,0.000002724093,0.00002948149,0.0002813769],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.015811,"threshold_uncertainty_score":0.4663314,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01177796719087136,"score_gpt":0.2656573748553598,"score_spread":0.2538794076644885,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}