{"id":"W2259090724","doi":"10.1371/journal.pone.0147653","title":"Cog-Wheel Octameric Structure of RS1, the Discoidin Domain Containing Retinal Protein Associated with X-Linked Retinoschisis","year":2016,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"National Eye Institute; Natural Sciences and Engineering Research Council of Canada; National Institutes of Health; Canadian Institutes of Health Research; Macula Vision Research Foundation","keywords":"Retinoschisis; Discoidin domain; Retinal; Retina; Retinal degeneration; Biology; Cell biology; Chemistry; Anatomy; Neuroscience; Biochemistry; Retinal detachment; Signal transduction","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006817817,0.0002524506,0.0001826694,0.0002825185,0.0002928033,0.0004300796,0.0002170876,0.0002425576,0.001087576],"category_scores_gemma":[0.0001182013,0.00015831,0.0002284509,0.000179799,0.0002306514,0.0002587072,0.0001893711,0.0002319941,0.0003281194],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003948326,"about_ca_system_score_gemma":0.0002633972,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001598635,"about_ca_topic_score_gemma":0.001708098,"domain_scores_codex":[0.9999626,0.000004075166,0.000002550215,0.00001497516,0.000009436422,0.00000645385],"domain_scores_gemma":[0.999896,0.000007159395,0.00004242297,0.00001049107,0.00001352985,0.00003027542],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002660356,0.00003845497,0.005889259,0.0001585328,0.00003817075,0.0009377565,0.0001708747,0.001973457,0.9797888,0.002131148,0.0004391862,0.008168207],"study_design_scores_gemma":[0.00004028566,0.0004892389,0.1394365,0.00007076938,0.0001644975,0.005890327,0.0006717025,0.05195103,0.7619533,0.001847537,0.03737434,0.0001104088],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9901314,0.0009219238,0.007192742,0.00009015505,0.00002334744,0.00001736557,0.0002394915,0.0001945715,0.001189031],"genre_scores_gemma":[0.9920561,0.0002918165,0.005511269,0.00002467758,0.000003255439,0.00000642168,0.0003641701,0.00001649426,0.00172583],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001598635,"threshold_uncertainty_score":0.003638327,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01219342925073085,"score_gpt":0.1965530457372166,"score_spread":0.1843596164864858,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}