{"id":"W2259285077","doi":"10.1016/j.devcel.2015.12.027","title":"Maternal DNA Methylation Regulates Early Trophoblast Development","year":2016,"lang":"en","type":"article","venue":"Developmental Cell","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":164,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Biotechnology and Biological Sciences Research Council; Wellcome; Royal Society; Medical Research Council; Canadian Institutes of Health Research; Wellcome Trust","keywords":"Biology; DNA methylation; Trophoblast; Methylation; DNA; Cell biology; Genetics; Computational biology; Placenta; Gene; Pregnancy; Fetus; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001066839,0.0001963554,0.0001361456,0.0002406982,0.0001416327,0.0002718569,0.0001348345,0.0001747442,0.0007648945],"category_scores_gemma":[0.0001941961,0.0001557674,0.0001062961,0.0001297494,0.0002383371,0.0001442425,0.0002944772,0.0003062761,0.0003452983],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004132485,"about_ca_system_score_gemma":0.0002306479,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001298838,"about_ca_topic_score_gemma":0.001974041,"domain_scores_codex":[0.9999079,0.0000159385,0.000005803599,0.00002622873,0.00002678172,0.00001729178],"domain_scores_gemma":[0.9999194,0.00001817747,0.0000262774,0.000008122205,0.00001043994,0.00001751787],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005183127,0.000001801314,0.000938552,0.00001153531,0.000002227152,0.00004285635,0.00002228946,0.00005100006,0.9971265,0.0001566072,0.00001602346,0.001578792],"study_design_scores_gemma":[0.00001422931,0.0001031583,0.06015464,0.00001280002,0.0000207421,0.0003985519,0.00006265704,0.001594274,0.9319613,0.0006058153,0.005062046,0.00000980294],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9841209,0.00519499,0.006146067,0.0001549176,0.00001989994,0.00001269891,0.0004209449,0.0001645689,0.003765078],"genre_scores_gemma":[0.994628,0.001534706,0.002001106,0.00002709785,0.000005906959,0.000008324875,0.0002036549,0.0000230148,0.00156816],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001298838,"threshold_uncertainty_score":0.002998352,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007948750264812727,"score_gpt":0.20527153069588,"score_spread":0.1973227804310672,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}