{"id":"W2259380452","doi":"10.1089/aid.2014.5252.abstract","title":"Activation of Toll-like Receptor 2 (TLR2) Heterodimers by HIV-1 Proteins Significantly Increases HIV Infection and Inflammation","year":2014,"lang":"en","type":"article","venue":"AIDS Research and Human Retroviruses","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"McMaster University; McMaster University Medical Centre","funders":"","keywords":"TLR2; Human immunodeficiency virus (HIV); Inflammation; Receptor; Toll; Toll-like receptor; Immunology; Biology; Medicine; Virology; Innate immune system; Internal medicine; TLR4","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003416139,0.0005206237,0.0003421233,0.0003166032,0.0003014777,0.0007639443,0.0001379398,0.0005041293,0.004728172],"category_scores_gemma":[0.0003541754,0.000236698,0.0003676453,0.0002274151,0.0001932758,0.0003594793,0.0004542079,0.001194544,0.0006024902],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002306252,"about_ca_system_score_gemma":0.0002396339,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002645169,"about_ca_topic_score_gemma":0.0003915516,"domain_scores_codex":[0.9993116,0.0002290773,0.00003549219,0.00006301388,0.0001419808,0.0002188817],"domain_scores_gemma":[0.9997621,0.00005085814,0.00004972059,0.00003437823,0.00002908605,0.00007387801],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009563603,0.0002827227,0.002384348,0.000124612,0.00003739776,0.0001392371,0.00003376626,0.00006377057,0.9890696,0.0001789401,0.0004306393,0.006298691],"study_design_scores_gemma":[0.0001285276,0.002807737,0.08170551,0.00007190785,0.0001021554,0.001364458,0.0004598143,0.001090646,0.9030904,0.0004012366,0.00875257,0.00002506459],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9849679,0.00953297,0.001068691,0.0003131107,0.0002402137,0.00003721455,0.0004415561,0.00007817168,0.003320209],"genre_scores_gemma":[0.9923422,0.002343106,0.0008238961,0.000220897,0.0001176302,0.00004920561,0.0006237966,0.00001020541,0.003468991],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004728172,"threshold_uncertainty_score":0.01581728,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02491199972415111,"score_gpt":0.2899691865438012,"score_spread":0.2650571868196501,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}