{"id":"W2259441487","doi":"10.1200/jco.2006.24.18_suppl.18579","title":"Assessing rectal toxicity in a pilot study using intrarectal amifostine and concurrent radiation","year":2006,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Effects of Radiation Exposure","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; Ontario Institute for Cancer Research","funders":"","keywords":"Medicine; Amifostine; Prostate cancer; Rectum; Toxicity; Proctitis; Radiation proctitis; Radiation therapy; Urology; Quality of life (healthcare); Colorectal cancer; Internal medicine; Surgery; Oncology; Cancer; Ulcerative colitis; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[{"model":"gemma","categories":[],"domain":null,"study_design":"observational","genre":"empirical","about_ca_system":false,"about_ca_topic":false,"confidence":"low","status":"direct model label, unvalidated"},{"model":"gpt","categories":[],"domain":null,"study_design":"design_other","genre":"empirical","about_ca_system":false,"about_ca_topic":false,"confidence":"low","status":"direct model label, unvalidated"}],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002830888,0.0007818103,0.0008860438,0.0002939347,0.0004624673,0.0003800782,0.000528291,0.0005005198,0.001812784],"category_scores_gemma":[0.002086555,0.000365547,0.000997216,0.0004088898,0.0006875723,0.0004153896,0.0004034775,0.001320327,0.0004321834],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005463494,"about_ca_system_score_gemma":0.00114366,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00124973,"about_ca_topic_score_gemma":0.002055778,"domain_scores_codex":[0.9985695,0.0008814844,0.00007852224,0.000162375,0.0001952521,0.0001128057],"domain_scores_gemma":[0.9979243,0.0005638471,0.0003303481,0.0003242411,0.0002355375,0.0006217156],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"nonrandomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.2284425,0.2913312,0.2555577,0.0005924855,0.001238749,0.001644714,0.001936561,0.001991972,0.1490497,0.0001120768,0.0008097384,0.06729273],"study_design_scores_gemma":[0.005337874,0.8991597,0.08779119,0.000007996218,0.0001794612,0.0005489137,0.0001800958,0.0005792906,0.005690928,0.00001655242,0.0004936571,0.00001440145],"study_design_candidate":"nonrandomized_trial","study_design_consensus":"nonrandomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9992669,0.00007408836,0.0002026225,0.00001622757,0.000007943402,0.0002610655,0.00003873892,0.000005887193,0.0001265209],"genre_scores_gemma":[0.9975406,0.0001362415,0.001057647,0.000104777,0.00003573909,0.000550167,0.0002536872,0.000005525734,0.0003155596],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002830888,"threshold_uncertainty_score":0.01497138,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1553101319589364,"score_gpt":0.5034021511919993,"score_spread":0.3480920192330629,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}