{"id":"W2259461267","doi":"10.1016/j.jinf.2016.01.010","title":"Defining immunological dysfunction in sepsis: A requisite tool for precision medicine","year":2016,"lang":"en","type":"review","venue":"Journal of Infection","topic":"Sepsis Diagnosis and Treatment","field":"Medicine","cited_by":96,"is_retracted":false,"has_abstract":false,"ca_institutions":"Toronto General Hospital; University Health Network","funders":"Instituto de Salud Carlos III","keywords":"Sepsis; Immunology; Immunosuppression; Immune system; Acquired immune system; Immune dysregulation; Medicine; Disease; Innate immune system; Antibody; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003379732,0.001154513,0.004544946,0.002939966,0.0004240238,0.002650852,0.001653652,0.002197048,0.00185182],"category_scores_gemma":[0.005128548,0.0005134514,0.001211717,0.001861422,0.001388559,0.002849556,0.001455935,0.005019633,0.0008861649],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001086698,"about_ca_system_score_gemma":0.003377333,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001490682,"about_ca_topic_score_gemma":0.002992854,"domain_scores_codex":[0.998906,0.0002753103,0.0002462731,0.0001317059,0.0003863719,0.00005432028],"domain_scores_gemma":[0.9944483,0.003946013,0.0004794282,0.0001289322,0.0008525485,0.0001447686],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000130679,0.0001101671,0.0006372778,0.04293809,0.0004824637,0.0002026895,0.00009070354,0.0004172325,0.0009370543,0.007447424,0.02425481,0.9223514],"study_design_scores_gemma":[0.00009082408,0.000244326,0.002492151,0.03755198,0.001249135,0.001567034,0.0002604344,0.0003999241,0.0007501005,0.01432452,0.9409653,0.0001042092],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00003794872,0.9984655,0.0001809243,0.0008917809,0.00022917,0.000003771282,0.00001075547,0.000004612887,0.0001755174],"genre_scores_gemma":[0.0007585767,0.9970359,0.0006049675,0.0008833827,0.0005863574,0.000008473534,0.00001824388,0.000001349549,0.0001027953],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004544946,"threshold_uncertainty_score":0.01787394,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1168699520500464,"score_gpt":0.4210957285076994,"score_spread":0.304225776457653,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}