{"id":"W2259632429","doi":"10.1021/acs.analchem.5b04536","title":"Intrinsically Labeled Fluorescent Oligonucleotide Probes on Quantum Dots for Transduction of Nucleic Acid Hybridization","year":2016,"lang":"en","type":"article","venue":"Analytical Chemistry","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Förster resonance energy transfer; Chemistry; Fluorescence; Oligonucleotide; Quantum dot; Nucleic acid; Intercalation (chemistry); Biosensor; Molecular beacon; Photochemistry; Molecule; DNA; Nanotechnology; Biochemistry; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005072588,0.0004957445,0.000547136,0.0002706352,0.0001904769,0.0003858861,0.0004985905,0.0006597441,0.001813184],"category_scores_gemma":[0.0004669614,0.0003079523,0.0003160067,0.0003460759,0.0002785311,0.0005260442,0.0004221914,0.000755185,0.0009897627],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004084391,"about_ca_system_score_gemma":0.0002047701,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002399269,"about_ca_topic_score_gemma":0.0004983703,"domain_scores_codex":[0.999494,0.0001134001,0.00003856796,0.0001355799,0.0001552976,0.00006322259],"domain_scores_gemma":[0.9998285,0.00005946744,0.00002428221,0.00002588695,0.00004739951,0.00001435598],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001496208,0.000008999556,0.00003603525,0.00006776711,0.00000277179,0.00002835361,0.00001788571,0.0001549645,0.9955453,0.0007320723,0.0000652905,0.003325764],"study_design_scores_gemma":[0.000004795263,0.0000898555,0.0002353888,0.00001071837,0.000006821405,0.0001128331,0.000006150842,0.002785932,0.9891651,0.0002624071,0.007309968,0.000009920287],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.3233673,0.006975127,0.6595409,0.0003279519,0.0003523056,0.0004279548,0.0007536801,0.001977939,0.006276932],"genre_scores_gemma":[0.5679181,0.006425628,0.412175,0.0003886367,0.00006711222,0.0005920234,0.001069309,0.0002438336,0.01112039],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.001813184,"threshold_uncertainty_score":0.006065667,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009472569000952885,"score_gpt":0.2602191012242675,"score_spread":0.2507465322233146,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}