{"id":"W2259890699","doi":"10.1093/ijnp/pyw011","title":"Emotional Impairment and Persistent Upregulation of mGlu<sub>5</sub>Receptor following Morphine Abstinence: Implications of an mGlu<sub>5</sub>-MOPr Interaction","year":2016,"lang":"en","type":"article","venue":"The International Journal of Neuropsychopharmacology","topic":"Neurotransmitter Receptor Influence on Behavior","field":"Neuroscience","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"Research Councils UK","keywords":"Abstinence; Addiction; Opioid; Metabotropic glutamate receptor; Morphine; Psychology; Opioid receptor; Metabotropic receptor; Medicine; Glutamate receptor; Pharmacology; Neuroscience; Psychiatry; Receptor; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004913299,0.0002693425,0.000348808,0.0004455826,0.0001203768,0.00004308195,0.000969536,0.00007880002,0.0001346291],"category_scores_gemma":[0.0002077204,0.0001917439,0.0003722162,0.000264358,0.0003621111,0.0008222747,0.0001229797,0.0003632815,0.0000196264],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001631899,"about_ca_system_score_gemma":0.0001060784,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003414567,"about_ca_topic_score_gemma":0.000001688321,"domain_scores_codex":[0.9968097,0.0004191471,0.001169974,0.0004274249,0.0008972334,0.0002765392],"domain_scores_gemma":[0.9970976,0.0005938443,0.001313164,0.000264081,0.0005497424,0.0001816364],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008301623,0.0005252228,0.001954505,0.00001054264,0.00008758486,0.00002746469,0.0002183493,0.0004290833,0.9748685,0.00008000197,0.0002816674,0.02068691],"study_design_scores_gemma":[0.002261655,0.0007416451,0.08548525,0.0001129242,0.0001198356,0.0009267819,0.00003398754,0.0002171071,0.909516,0.0002788958,0.0001486713,0.0001571923],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9881462,0.0000286678,0.0003724199,0.007609325,0.00332064,0.0003872298,0.00008509382,0.00002538333,0.00002504731],"genre_scores_gemma":[0.9982221,0.0003118172,0.0001131809,0.000927552,0.000349061,0.00002505202,0.000003483609,0.00003802643,0.000009778795],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08353075,"threshold_uncertainty_score":0.7819088,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02870797481477062,"score_gpt":0.3240922592119153,"score_spread":0.2953842843971446,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}