{"id":"W2260880624","doi":"10.1007/s10545-015-9903-z","title":"Biosynthesis of glycosaminoglycans: associated disorders and biochemical tests","year":2015,"lang":"en","type":"review","venue":"Journal of Inherited Metabolic Disease","topic":"Proteoglycans and glycosaminoglycans research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":60,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Centre Hospitalier Universitaire Sainte-Justine","funders":"","keywords":"Dermatan sulfate; Keratan sulfate; Glycosaminoglycan; Biochemistry; Heparan sulfate; Glycosyltransferase; Proteoglycan; Serine; Iduronic acid; Chondroitin sulfate; Disaccharide; Tetrasaccharide; Biosynthesis; Sulfatase; Chondroitin; Chemistry; Linker; Enzyme; Extracellular matrix","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0009528891,0.0005826827,0.002103341,0.0005113386,0.00005287385,0.00005102132,0.0007172274,0.0005247001,0.00002402071],"category_scores_gemma":[0.002309382,0.0004530636,0.0008944852,0.0006334589,0.0003949655,0.00001643054,0.0002887656,0.000492743,0.000002706585],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004947946,"about_ca_system_score_gemma":0.001884268,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002305389,"about_ca_topic_score_gemma":0.000008918286,"domain_scores_codex":[0.9965109,0.0004880858,0.001326975,0.0004674407,0.0007226907,0.000483915],"domain_scores_gemma":[0.9964377,0.00008741864,0.001335847,0.0005754164,0.0006438122,0.0009197688],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004835147,0.0008060968,0.0001711498,0.004109859,0.00163754,0.00006590554,0.00002626678,0.000001455028,0.002686004,0.00002861341,0.004965715,0.9850179],"study_design_scores_gemma":[0.0009548665,0.00034288,0.0003430395,0.0028975,0.001742451,0.00006158374,0.00002531889,0.000004088347,0.0002760309,0.00007704041,0.9928015,0.0004737145],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0117265,0.986744,0.00002958751,0.00005262468,0.0001646877,0.000528666,0.0006533486,0.000007063192,0.00009356164],"genre_scores_gemma":[0.003860166,0.9949389,0.0003244218,0.00003699654,0.0003560609,0.00003586846,0.0002044419,0.00009558081,0.0001475801],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9878358,"threshold_uncertainty_score":0.9997921,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03406659278191691,"score_gpt":0.3403096015881141,"score_spread":0.3062430088061972,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}