{"id":"W2261355487","doi":"10.1074/jbc.m115.688523","title":"Dissecting the Molecular Roles of Histone Chaperones in Histone Acetylation by Type B Histone Acetyltransferases (HAT-B)","year":2015,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Cancer Research","funders":"National Institute of General Medical Sciences; National Cancer Institute; National Institute on Aging; National Institutes of Health","keywords":"Histone H4; Histone H1; Histone H2A; Histone acetyltransferase; SAP30; Histone methyltransferase; Histone octamer; Histone code; Histone Acetyltransferases; Histone; Histone H3; Chaperone (clinical); Biology; Histone deacetylase 2; Biochemistry; Molecular biology; Chemistry; Cell biology; Histone deacetylase; Nucleosome; DNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002192986,0.0002242157,0.0001929503,0.0001089155,0.0001602684,0.000225708,0.0001913318,0.000260886,0.000799274],"category_scores_gemma":[0.00006286737,0.0001439641,0.0002176604,0.0001093846,0.0001471347,0.0003136439,0.0001225254,0.0002945508,0.0002008107],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002372097,"about_ca_system_score_gemma":0.0001294125,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008222907,"about_ca_topic_score_gemma":0.001156656,"domain_scores_codex":[0.9999238,0.00001164022,0.000004966704,0.00001792667,0.0000211538,0.00002045102],"domain_scores_gemma":[0.9999547,0.00001056518,0.00001003336,0.000003467256,0.000006192269,0.00001503745],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001429865,0.00002969883,0.0003231647,0.00003551686,0.000005480189,0.00001734207,0.000005834693,0.00008795656,0.9976932,0.0001047992,0.00002788223,0.001526108],"study_design_scores_gemma":[0.00002703462,0.0003686435,0.008083357,0.000006254067,0.00002811576,0.0001566178,0.00002819032,0.002405164,0.9856429,0.00008875062,0.003158364,0.000006752863],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9914525,0.004510198,0.003044639,0.0001439111,0.00002660968,0.00001653128,0.0001320922,0.00003147625,0.0006421354],"genre_scores_gemma":[0.9903044,0.002884504,0.00484209,0.0000715202,0.00003265122,0.00001730753,0.0002385155,0.000008468416,0.00160052],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008222907,"threshold_uncertainty_score":0.002673805,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01550895742505588,"score_gpt":0.281766175171691,"score_spread":0.2662572177466351,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}