{"id":"W2261977941","doi":"10.1039/c5ra24684a","title":"3-(5-(Benzylideneamino)thiazol-3-yl)-2H-chromen-2-ones: a new class of alkaline phosphatase and ecto-5′-nucleotidase inhibitors","year":2016,"lang":"en","type":"article","venue":"RSC Advances","topic":"Alkaline Phosphatase Research Studies","field":"Medicine","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"Higher Education Commission, Pakistan","keywords":"Alkaline phosphatase; 5'-nucleotidase; Class (philosophy); Chemistry; Phosphatase; Stereochemistry; Biochemistry; Enzyme; Computer science; Artificial intelligence","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004608219,0.0004208068,0.0009839359,0.0002328653,0.0001480398,0.00002269355,0.0001964764,0.0001162002,0.0003821958],"category_scores_gemma":[0.001538507,0.000272002,0.0001591336,0.0003772335,0.0006635478,0.0006572352,0.000316965,0.0002178051,0.0001081567],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001036016,"about_ca_system_score_gemma":0.000320187,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002715553,"about_ca_topic_score_gemma":0.000142495,"domain_scores_codex":[0.9968944,0.00006753962,0.0008059954,0.0006946381,0.0008540143,0.0006833741],"domain_scores_gemma":[0.9974176,0.0006953901,0.0003481216,0.0006323823,0.0002823223,0.0006242331],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.005233844,0.001663627,0.05434994,0.003413603,0.001565032,0.001360818,0.001803381,0.00002311331,0.1397211,0.007984571,0.09466457,0.6882164],"study_design_scores_gemma":[0.01556288,0.002479602,0.01121768,0.003011619,0.0004257084,0.0002072209,0.001304043,0.0001252458,0.4686775,0.005265391,0.4906487,0.001074403],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7504074,0.2310926,0.00138399,0.01143826,0.0006875749,0.001951234,0.0011665,0.0003582535,0.001514224],"genre_scores_gemma":[0.9698128,0.02349899,0.003293705,0.000326433,0.0006816891,0.00004678934,0.00007178981,0.00006934919,0.002198488],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.687142,"threshold_uncertainty_score":0.9999732,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01779555892935174,"score_gpt":0.3070302378854904,"score_spread":0.2892346789561387,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}